(1R,9S)-11-benzoyl-5-(furan-2-yl)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: (1R,9S)-11-benzoyl-5-(furan-2-yl)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one
• 化学式: C₂₂H₂₀N₂O₃
• 分子量: 360.4
• InChiKey: XXLFEKIIWOIUFR-DOTOQJQBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  27
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  53.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Extract for treating wrinkles and/or fine lines
  申请人：Avon Products, Inc.

  公开号：US10251831B2

  公开（公告）日：2019-04-09

  Cosmetic compositions comprising one or more paxillin stimulators and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The paxillin stimulators and combinations thereof are believed to have modulatory activity against at least one biochemical pathway implicated in skin aging.

  本发明公开了包含一种或多种 paxillin 刺激剂的化妆品组合物以及使用此类组合物为皮肤带来抗衰老功效的方法。据信，paxillin 刺激剂及其组合具有针对至少一种与皮肤老化有关的生化途径的调节活性。
• PAXILLIN STIMULATING COMPOSITIONS AND COSMETIC USES THEREOF
  申请人：Avon Products, Inc.

  公开号：EP2516429B1

  公开（公告）日：2020-06-24
• USE OF TILIACORA TRIANDRA IN COSMETICS AND COMPOSITIONS THEREOF
  申请人：Avon Products, Inc.

  公开号：EP2588062B1

  公开（公告）日：2019-05-29
• Paxillin Stimulating Compositions and Cosmetic Uses Thereof
  申请人：ZHENG Qian

  公开号：US20110151029A1

  公开（公告）日：2011-06-23

  Cosmetic compositions comprising one or more paxillin stimulators and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The paxillin stimulators and combinations thereof are believed to have modulatory activity against at least one biochemical pathway implicated in skin aging.
• Use of Tiliacora Triandra in Cosmetics and Compositions Thereof
  申请人：Ptchelintsev Dmitri S.

  公开号：US20120003331A1

  公开（公告）日：2012-01-05

  The present disclosure relates to compositions and methods for treating, preventing and improving the condition and aesthetic appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, where the compositions include natural plant constituents which increase expression levels genes, collagen replacement and retention, and cell proliferation of epidermis and dermis associated with the dermatological signs of aging. The compositions of the invention are topically applied to the skin, or are delivered by directed means to a site in need thereof, once daily in an amount effective in improving the condition and aesthetic appearance of skin.