1-乙烯基磺酰基辛烷 | 28345-91-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 中文名称: 1-乙烯基磺酰基辛烷
• 英文名称: octyl vinyl sulfone
• 英文别名: Octane, 1-(ethenylsulfonyl)-；1-ethenylsulfonyloctane
• CAS: 28345-91-7
• 化学式: C₁₀H₂₀O₂S
• mdl: MFCD02667418
• 分子量: 204.334
• InChiKey: KWFGVRYYABRBHO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2904100000

反应信息

• 作为反应物：
  描述：

  3-butylthio-2-aminopropan-1-ol 、 1-乙烯基磺酰基辛烷 生成 3-butylthio-2-<(β-octylsulfonyl)ethylamino>propan-1-ol
  参考文献：
  名称：

  DERZHINSKIJ, A. R.;KALUGIN, V. E.;PRILEZHAEVA, E. N., IZV. AN CCCP. CEP. XIM., 1985, N 7, 1623-1634

  摘要：

  DOI：

文献信息

• Heteroaryl compounds and uses thereof
  申请人：Celgene CAR LLC

  公开号：US10774052B2

  公开（公告）日：2020-09-15

  The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

  本发明提供了化合物、其药学上可接受的组合物及其使用方法。
• Functional sulfur-containing compounds. Communication 7. Reactions of 2,3-epoxypropyl alkyl sulfides, sulfoxides, and sulfones with alkoxides and amines
  作者：A. R. Derzhinskii、V. E. Kalugin、E. N. Prilezhaeva

  DOI：10.1007/bf00950153

  日期：1985.7
• DERZHINSKIJ, A. R.;KALUGIN, V. E.;PRILEZHAEVA, E. N., IZV. AN CCCP. CEP. XIM., 1985, N 9, 2090-2094
  作者：DERZHINSKIJ, A. R.、KALUGIN, V. E.、PRILEZHAEVA, E. N.

  DOI：——

  日期：——
• COVALENT INHIBITORS OF DUAL OXIDASE 1 (DUOX 1)
  申请人：The University of Vermont and State Agricultural College

  公开号：US20170128517A1

  公开（公告）日：2017-05-11

  The present invention generally relates to inhibitors of DUOX1. In some aspects, an inhibitor may be applied to a subject having or being at risk for asthma or other conditions. The inhibitor may be applied by various techniques, such as pulmonary or topical delivery. In some embodiments, the inhibitor may include a peptide or other moiety having a reactive electrophile. The reactive electrophile can target cysteine or other residues within DUOX1 to inhibit its activity, e.g., by covalently binding to the residue. Other non-limiting examples of suitable inhibitors include hydroxynonenal, curcumin, sulforaphane, cinnamaldehyde, dimethyl fumarate, or phenyl vinyl sulfonate. Other aspects of the invention are generally directed to methods of making or using such inhibitors, kits involving such inhibitors, devices or formulations containing such inhibitors, or the like.
• US4160846A
  申请人：——

  公开号：US4160846A

  公开（公告）日：1979-07-10