2,2,6,6-四甲基哌啶4-甲基苯磺酸盐 | 30680-88-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 2,2,6,6-四甲基哌啶4-甲基苯磺酸盐
• 英文名称: 2,2,6,6-tetarmethylpiperidinium p-toluenesulphonate
• 英文别名: 2,2,6,6-tetramethylpiperidinium tosylate；2,2,6,6-tetramethyl-piperidine; toluene-4-sulfonate；2,2,6,6-Tetramethyl-piperidin; Toluol-4-sulfonat；Piperidine, 2,2,6,6-tetramethyl-, p-toluenesulfonate；4-methylbenzenesulfonic acid;2,2,6,6-tetramethylpiperidine
• CAS: 30680-88-7
• 化学式: C₇H₈O₃S*C₉H₁₉N
• 分子量: 313.461
• InChiKey: YKKDFXKIOBJFNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.56
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  74.8
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2933399090

反应信息

• 作为产物：
  描述：

  2,2,6,6-四甲基哌啶氧化物 在 4-叔丁基苯硫酚 作用下， 以 乙腈 、 苯 为溶剂， 反应 0.5h， 生成 2,2,6,6-四甲基哌啶4-甲基苯磺酸盐
  参考文献：
  名称：

  Unexpected Deoxygenation of 2,2,6,6-Tetramethylpiperidine-1-Oxyl (TEMPO) by Thiyl Radicals through the Formation of Arylsulphinyl Radicals

  摘要：

  2,2,6,6-Tetramethylpiperidine-1-oxyl (TEMPO), upon reaction with thiophenols, undergoes deoxygenation leading mainly to the formation of tetramethylpiperidinium arylsulphinates and arylsulphonates. Other identified products of the reaction are aryldisulphides, 2,2,6,6-tetramethylpiperidine, S-aryl-arylthiosulphonates, N-arylsulphinyl- and N-arylsulphonyl-2,2,6,6-tetramethylpiperidine. The formation of the reaction products is discussed on the basis of the interaction of arylsulphinyl and arylsulphonyl radicals with TEMPO as well as on the basis of the evolution of the arylsulphinyl radical itself.

  DOI：

  10.1016/0040-4020(95)00800-n

文献信息

• 2,2,6,6-Tetramethylpiperidinium triflate (TMPT): a highly selective and self-separated catalyst for esterification
  作者：Lan Gao、Taoping Liu、Xiaochun Tao、Yongmin Huang

  DOI：10.1016/j.tetlet.2016.09.061

  日期：2016.11

  An eco-friendly and readily accessible 2,2,6,6-tetramethylpiperidinium triflate was found as highly-selective and self-separated catalyst for esterification under solvent-free condition. The X-ray crystallography revealed that it formed a ‘hydrophobic wall’ which could effectively eliminate the generated water from the reactive sites. Moreover, it could precipitate from the reaction system with excellent

  发现一种环保且易于获得的三氟甲磺酸2,2,6,6-四甲基哌啶鎓是在无溶剂条件下酯化的高选择性和自分离催化剂。X射线晶体学显示它形成了一个“疏水壁”，可以有效地消除反应位点产生的水。而且，它可以以优异的回收率（> 99％）从反应体系中沉淀出来，可以重复使用十次而活性没有任何显着损失。
• US3975357A
  申请人：——

  公开号：US3975357A

  公开（公告）日：1976-08-17
• Unexpected Deoxygenation of 2,2,6,6-Tetramethylpiperidine-1-Oxyl (TEMPO) by Thiyl Radicals through the Formation of Arylsulphinyl Radicals
  作者：Patricia Carloni、Elisabetta Damiani、Marco Iacussi、Lucedio Greci、Pierluigi Stipa、Daniele Cauzi、Corrado Rizzoli、Paolo Sgarabotto

  DOI：10.1016/0040-4020(95)00800-n

  日期：1995.11

  2,2,6,6-Tetramethylpiperidine-1-oxyl (TEMPO), upon reaction with thiophenols, undergoes deoxygenation leading mainly to the formation of tetramethylpiperidinium arylsulphinates and arylsulphonates. Other identified products of the reaction are aryldisulphides, 2,2,6,6-tetramethylpiperidine, S-aryl-arylthiosulphonates, N-arylsulphinyl- and N-arylsulphonyl-2,2,6,6-tetramethylpiperidine. The formation of the reaction products is discussed on the basis of the interaction of arylsulphinyl and arylsulphonyl radicals with TEMPO as well as on the basis of the evolution of the arylsulphinyl radical itself.