2,5-二氢-1,3-噻唑 | 24576-55-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑啉类
• 中文名称: 2,5-二氢-1,3-噻唑
• 英文名称: 2,5-dihydro-1,3-thiazole
• 英文别名: 5-H-thiazole；2,5-dihydro-thiazole；2,5-dihydrothiazole；Δ³-Dihydrothiazol
• CAS: 24576-55-4
• 化学式: C₃H₅NS
• 分子量: 87.1454
• InChiKey: JLPUISACQXFVRC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  37.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  12-(N-methyliminomethyl)-9,10-dimethyl-9,10-dihydro-11-thia-9,10-ethanoanthracene 生成 2,5-二氢-1,3-噻唑
  参考文献：
  名称：

  Arnaud, Roger; Pelloux-Leon, Nadia; Ripoll, Jean-Louis, Journal of the Chemical Society. Perkin transactions II, 1995, # 6, p. 1077 - 1086

  摘要：

  DOI：

文献信息

• Synthesis of 4H-3,3a-dihydrothiazolo[4,3-<i>b</i>]quinazolines
  作者：Emmanuel A. Adegoke、Babajide I. Alo、Oluwole B. Familoni

  DOI：10.1002/jhet.5570240122

  日期：1987.1

  Regiospecific synthesis of 4H-3,3a-dihydrothiazolo[4,3-b]quinazolines and 7-methyl-4H-3,3a-dihydrothiazolo[4,3-b]quinazolines IVa and IVb is described. The N-substituted thiazolidinecarboxylic acids Ia and Ib were converted to the corresponding acid chlorides, IIa and IIb but neither reacted with silver trifluoromethanesulphonate. The carboxylic acids Ic and Id were however, decarboxylated to the corresponding

  描述了4 H -3,3a-二氢噻唑并[4,3- b ]喹唑啉和7-甲基-4 H -3,3a-二氢噻唑并[4,3- b ]喹唑啉IVa和IVb的区域特异性合成。所述Ñ取代噻唑烷酸IA和磅被转化为相应的酰基氯，IIA和IIB但既不与三氟甲磺酸银反应。但是，使用三氯氧化磷将羧酸Ic和Id脱羧成相应的亚胺离子，得到了硝胺IIIa和IIIb。还原环化产生喹唑啉IVa和IVb。
• The rearrangement of α-imino-thioaldehydes into dihydro-1,3-thiazoles
  作者：Roger Arnaud、Nadia Pelloux-Léon、Jean-Louis Ripoll、Yannick Vallée

  DOI：10.1016/s0040-4039(00)74414-5

  日期：1994.11

  alpha-Imino-thioaldehydes were generated by retro-Diels-Alder reaction under flash vacuum thermolysis conditions. They were found to be unstable and cyclized to 2,3-dihydro-1,3-thiazoles. This cyclization was investigated by ab initio calculations.
• Arnaud, Roger; Chavant, Pierre-Yves; Hagoug, Fatiha, Phosphorus, Sulfur and Silicon and the Related Elements, 1994, vol. 96, # 1-4, p. 319 - 320
  作者：Arnaud, Roger、Chavant, Pierre-Yves、Hagoug, Fatiha、Pelloux-Leon, Nadia、Ripoll, Jean-Louis、Vallee, Yannick

  DOI：——

  日期：——