2,4-bis(4-chlorobenzyloxy)-6-(5H)-one-1,3,5-triazine | 918664-15-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 2,4-bis(4-chlorobenzyloxy)-6-(5H)-one-1,3,5-triazine
• 英文别名: 4,6-Bis[(4-chlorophenyl)methoxy]-1,3,5-triazin-2(1H)-one；4,6-bis[(4-chlorophenyl)methoxy]-1H-1,3,5-triazin-2-one
• CAS: 918664-15-0
• 化学式: C₁₇H₁₃Cl₂N₃O₃
• 分子量: 378.215
• InChiKey: ZVSXWAJONQVOAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  72.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  三聚氯氰 、 4-氯苯甲醇 在 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 以60%的产率得到2,4-bis(4-chlorobenzyloxy)-6-(5H)-one-1,3,5-triazine
  参考文献：
  名称：

  Synthesis and antibacterial activity of various substituted s-triazines

  摘要：

  Series of substituted-s-triazines (1-22) were synthesized and evaluated for their in vitro antibacterial activity against six representative Gram-positive and Gram-negative bacterial strains. Many compounds have displayed comparable antibacterial activity against Bacillus sphaericus and significantly active against other tested organisms with reference to streptomycin. (c) 2006 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2006.05.013

文献信息

• Synthesis and antibacterial activity of various substituted s-triazines
  作者：K. Srinivas、U. Srinivas、K. Bhanuprakash、K. Harakishore、U.S.N. Murthy、V. Jayathirtha Rao

  DOI：10.1016/j.ejmech.2006.05.013

  日期：2006.11

  Series of substituted-s-triazines (1-22) were synthesized and evaluated for their in vitro antibacterial activity against six representative Gram-positive and Gram-negative bacterial strains. Many compounds have displayed comparable antibacterial activity against Bacillus sphaericus and significantly active against other tested organisms with reference to streptomycin. (c) 2006 Elsevier Masson SAS. All rights reserved.