di(n-pentyl)phosphine | 24674-42-8

• 分子结构分类: 有机化合物 - 有机磷化合物
• 英文名称: di(n-pentyl)phosphine
• 英文别名: dipentylphosphine；bispentylphosphine；Di-n-amylphosphin；dipentylphosphane
• CAS: 24674-42-8
• 化学式: C₁₀H₂₃P
• 分子量: 174.266
• InChiKey: LEYRKQOMKMSLJQ-UHFFFAOYSA-N

物化性质

• 沸点：
  110-115 °C(Press: 18-20 Torr)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  11
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  di(n-pentyl)phosphine 在 双氧水 作用下， 以 环己烷 为溶剂， 反应 10.0h， 以76.2%的产率得到dipentylphosphinic acid
  参考文献：
  名称：

  一种二烷基次膦酸的制备方法

  摘要：

  本发明公开了一种二烷基次膦酸的制备方法，包括：将亚磷酸加入到反应釜中，加入催化剂，在170~190℃下热解产生磷化氢；将得到的磷化氢通入盛有烯烃的反应釜中在，引发剂存在下，加温加压，反应后得到二烷基膦化氢；将得到的二烷基膦化氢加入到溶剂中，搅拌条件下，加入双氧水，反应后得到二烷基次膦酸。本发明的一种二烷基次膦酸的制备方法，通过热解亚磷酸制取高纯度的磷化氢原料气体，再与各类烯烃进行自由基加成反应，制取高纯度、高品位、高附加值的二烷基膦化氢，再以二烷基膦化氢作为原料，进行后续的可控氧化，制取各种类型的二烷基次膦酸，操作步骤简单，操作条件温和。

  公开号：

  CN112142782A
• 作为产物：
  描述：

  正戊基溴化镁 在 cis-2,10-dimethyl<1,2,3>benzothiadiphospholo<2,3-b><1,2,3>benzothiadiphosphole 、 盐酸 作用下， 以 四氢呋喃 为溶剂， 生成 di(n-pentyl)phosphine
  参考文献：
  名称：

  High Atom-Economical One-Pot Synthesis of Secondary Phosphines and Their Borane Complexes Using Recycling Phosphorus Donor Reagent

  摘要：

  A general new method for the one-pot preparation of secondary phosphines 11 and in situ generation of their borane complexes 12 is described. This method consists of the sequential addition, at room temperature, of equivalent amounts of (RMgBr)-Mg-1 and (RMgBr)-Mg-2 to 1 equiv of the phosphorus atom donor reagent 1. Final treatment with water gives secondary phosphines (RRPH)-R-1-P-2 (or the corresponding phosphine-borane complexes if treated with BH3-THF) and the end product 6, which can be recycled.

  DOI：

  10.1021/ol060284d

文献信息

• [EN] IONIC LIQUID SOLVENTS<br/>[FR] SOLVANTS LIQUIDES IONIQUES
  申请人：UNIV DUBLIN CITY

  公开号：WO2010097412A1

  公开（公告）日：2010-09-02

  A chiral ionic compound comprising an alkyl substituted imidazolium or pyridinium cationic core having an alkyl ester side chain (-alkyl-C(O)O-) directly linked to the core and an associated counter anion, characterized in that the -O- atom of the ester side chain is linked to an alpha, a beta or a gamma hydroxycarboxylic acid functionality via the alpha, beta or gamma hydroxy of the acid functionality and the hydroxycarboxylic acid functionality has at least one asymmetric carbon, or characterized in that an -N= atom of the alkyl substituted imidazolium or pyridinium cationic core is substituted with an alpha, a beta or a gamma hydroxy group of a alpha, a beta or a gamma hydroxycarboxylic acid functionality and the hydroxycarboxylic acid functionality has at least one asymmetric carbon. The chiral ionic liquids (CILs) may be used as novel solvents, in particular for organic synthesis. The CILs have the potential to induce asymmetry into substrates or catalysts in a variety of organic transformations. A number of the compounds have low antimicrobial and low antifungal toxicities and are also biodegradable CILs.

  一种手性离子化合物，包括具有烷基取代的咪唑或吡啶阳离子核心，其具有直接连接到核心的烷基酯侧链（-烷基-C（O）O-）和相关的对应阴离子，其特征在于酯侧链的-O-原子通过α、β或γ羟基羧酸功能与羧酸功能的α、β或γ羟基相连，且羟基羧酸功能具有至少一个不对称碳，或者其特征在于烷基取代的咪唑或吡啶阳离子核心的-N=原子被α、β或γ羟基羧酸功能的α、β或γ羟基取代，且羟基羧酸功能具有至少一个不对称碳。这种手性离子液体（CILs）可用作新型溶剂，特别适用于有机合成。这些CILs有潜力在各种有机转化中向底物或催化剂引入不对称性。其中一些化合物具有低抗菌和低抗真菌毒性，并且也是可生物降解的CILs。
• PHOSPHORUS-CONTAINING CATALYSTS
  申请人：AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

  公开号：US20160207034A1

  公开（公告）日：2016-07-21

  The invention provides compounds of general structure I: (Ar 1 —Ar 2 —Ar 3 -E-P(=D)R 2 -) n M m X n L n ″. In this structure: •Ar 1 , Ar 2 and Ar 3 are aromatic groups wherein: —Ar 1 and Ar 3 are in a 1,3 relationship on Ar 2 , —each of Ar 1 , Ar 2 and Ar 3 optionally comprises one or more ring substituents of formula YR′ r wherein each Y independently is absent or is O, S, B, N or Si and each R′ is independently H, halogen, alkyl, cycloalkyl, aryl or heteroaryl and r is 1, 2 or 3, where r is 1 if Y is absent or is O or S, 2 if Y is B or N and 3 if Y is Si, —Ar 1 , Ar 2 and Ar 3 are each independently carbocyclic or heterocyclic and each is independently monocyclic, bicyclic or polycyclic and each ring of each of Ar 1 , Ar 2 and Ar 3 independently has 5, 6 or 7 ring atoms; •E is absent or is selected from the group consisting of O, S, NR″, SiR″ 2 , AsR″ 2 and CR″ 2 ; •M is a complexing metal; •X is selected from the group consisting of H, F, Br, CI, I, OTf, dba (dibenzylidene acetone), OC(═O)CF 3 and OAc; •L is selected from the group consisting of PR″ 2 , NR″ 2 , OR″, SR″, SiR″ 3 , AsR″ 3 , alkene, alkyne, aryl and heteroaryl, each of said alkene, alkyne, aryl and heteroaryl being optionally substituted, for example with one or more halogens and/or with one or more R groups as defined herein; •each R is independently alkyl, cycloalkyl, heterocyclyl, heterocycloalkyl, aryl or -, heteroaryl; •D is absent or is ═S or —O or —Z-linker-Z—, where each Z independently is O or NH or N-alkyl and linker is an alkyl chain of 2-5 carbon atoms in length; •each R″ is independently H, alkyl, cycloalkyl, heterocycloalkyl, aryl or heteroaryl, each other than H being optionally substituted, or R″ 2 is —Z-linker-Z— as defined above; and •m is 0 or 1 or 2; wherein if m is 0, n is 1, n′ and n″ are 0 and -- is absent; and if m is 1 or 2, n is 1 or 2 and n′ and n″ are integers such that the coordination sphere of M is filled, and D is absent.

  该发明提供了一般结构I的化合物：（Ar1—Ar2—Ar3-E-P（=D）R2-）nMmXnLn″。在这个结构中： •Ar1，Ar2和Ar3是芳香族基团，其中：—Ar1和Ar3在Ar2上呈1,3关系，—Ar1，Ar2和Ar3中的每一个可选地包括一个或多个环取代基，其化学式为YR′r，其中每个Y独立地不存在或为O、S、B、N或Si，每个R′独立地为H、卤素、烷基、环烷基、芳基或杂芳基，r为1、2或3，其中如果Y不存在或为O或S，则r为1，如果Y为B或N，则r为2，如果Y为Si，则r为3，—Ar1，Ar2和Ar3分别独立地为碳环或杂环，每个分别独立地为单环、双环或多环，每个Ar1，Ar2和Ar3的每个环独立地具有5、6或7个环原子； •E不存在或从O、S、NR″、SiR″2、AsR″2和CR″2组成的群体中选择； •M是络合金属； •X从H、F、Br、Cl、I、OTf、dba（双苯亚乙酮）、OC（═O）CF3和OAc组成的群体中选择； •L从PR″2、NR″2、OR″、SR″、SiR″3、AsR″3、烯烃、炔烃、芳基和杂芳基组成的群体中选择，所述的每个烯烃、炔烃、芳基和杂芳基可选地被取代，例如用一个或多个卤素和/或如本文所定义的一个或多个R基取代； •每个R独立地为烷基、环烷基、杂环烷基、杂环烷基、芳基或-、杂芳基； •D不存在或为═S或—O或—Z-连接-Z—，其中每个Z独立地为O或NH或N-烷基，连接体为长度为2-5个碳原子的烷基链； •每个R″独立地为H、烷基、环烷基、杂环烷基、芳基或杂芳基，除H外的每个均可选地被取代，或R″2为—Z-连接-Z—如上所定义；和 •m为0或1或2；其中如果m为0，n为1，n′和n″为0且--不存在；如果m为1或2，n为1或2，n′和n″为整数，使得M的配位球填满，并且D不存在。
• Mononuclear iron complex and organic synthesis reaction using same
  申请人：KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

  公开号：US10363551B2

  公开（公告）日：2019-07-30

  A mononuclear iron bivalent complex having iron-silicon bonds, which is represented by formula (1), can exhibit an excellent catalytic activity in at least one reaction selected from three reactions, i.e., a hydrosilylation reaction, a hydrogenation reaction and a reaction for reducing a carbonyl compound. (In the formula, R1 to R6 independently represent a hydrogen atom, an alkyl group which may be substituted by X, or the like; X represents a halogen atom, or the like; L1 represents at least one two-electron ligand selected from an isonitrile ligand, an amine ligand, an imine ligand, a nitrogenated heterocyclic ring, a phosphine ligand, a phosphite ligand and a sulfide ligand, wherein, when multiple L1's are present, two L1's may be bonded to each other; L2 represents a two-electron ligand that is different from a CO ligand or the above-mentioned L1, wherein, when multiple L2's are present, two L2's may be bonded to each other; and m1 represents an integer of 1 to 4 and m2 represents an integer of 0 to 3, wherein the sum total of m1 and m2 (i.e., m1+m2) satisfies 3 or 4.)

  具有铁-硅键的单核二价铁络合物，其由公式（1）表示，可以在三个反应中选择至少一个反应表现出优异的催化活性，即硅氢化反应、氢化反应和还原羰基化合物的反应。 （在公式中，R1至R6独立代表氢原子、可能被X取代的烷基团等；X代表卤素原子等；L1代表至少一种从异腈配体、胺配体、亚胺配体、氮杂环、膦配体、亚磷酸盐配体和硫化物配体中选择的两电子配体，其中，当存在多个L1时，两个L1可以相互连接；L2代表与CO配体或上述L1不同的两电子配体，其中，当存在多个L2时，两个L2可以相互连接；m1代表1至4的整数，m2代表0至3的整数，其中m1和m2的总和（即m1+m2）满足3或4。）
• [EN] PROCESS FOR THE HYDROGENATION OF IMINES<br/>[FR] PROCÉDÉ D'HYDROGÉNATION D'IMINES
  申请人：CHEMINOVA AS

  公开号：WO2010094164A1

  公开（公告）日：2010-08-26

  A process is provided for the hydrogenation of imines with hydrogen under elevated pressure in the presence of iridium complexes as catalysts and one or more co-catalysts selected among compounds comprising a carbon-halogen bond. Further provided are novel ligands and metal complexes thereof useful for the catalytic hydrogenation of imines with hydrogen. The novel ligands are compounds of the formula (VII) or formula (VIII) in the form of racemates, mixtures of stereoisomers or optically pure stereoisomers, wherein the radicals are as defined in the specification.

  提供了一种在铱络合物存在下，在高压下利用氢气对亚胺进行加氢的方法，其中选择的一个或多个辅催化剂为包含碳-卤素键的化合物。还提供了用于催化亚胺与氢气加氢的新型配体和金属络合物。这些新型配体是根据式（VII）或式（VIII）的化合物，以外消旋体、立体异构体混合物或光学纯立体异构体的形式存在，其中基团如规范中所定义。
• PROCESS FOR THE HYDROGENATION OF IMINES
  申请人：Saaby Steen

  公开号：US20110077418A1

  公开（公告）日：2011-03-31

  A process is provided for the hydrogenation of imines with hydrogen under elevated pressure in the presence of iridium complexes as catalysts and one or more co-catalysts selected among compounds comprising a carbon-halogen bond. Further provided are novel ligands and metal complexes thereof useful for the catalytic hydrogenation of imines with hydrogen. The novel ligands are compounds of the formula (VII) or formula (VIII) in the form of racemates, mixtures of stereoisomers or optically pure stereoisomers wherein the radicals are as defined in the specification.

  提供了一种在铱络合物存在下，在高压下利用氢气对亚胺进行加氢的方法，并选择一种或多种在其中的协同催化剂，所述协同催化剂选自包含碳-卤素键的化合物。还提供了用于催化亚胺与氢气加氢的新型配体和金属络合物。这些新型配体是根据式（VII）或式（VIII）的化合物，以外消旋体、立体异构体混合物或光学纯立体异构体的形式存在，其中基团如规范中所定义。