pyruvic acid 2-thenoylhydrazone | 116250-26-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: pyruvic acid 2-thenoylhydrazone
• 英文别名: pyruvic acid thiophene-2-carboxylic hydrazone；pyruvic acid thiophenecarbonyl hydrazone；2-(Thiophene-2-carbonylhydrazinylidene)propanoic acid；2-(thiophene-2-carbonylhydrazinylidene)propanoic acid
• CAS: 116250-26-1
• 化学式: C₈H₈N₂O₃S
• 分子量: 212.229
• InChiKey: ILHWIZVDYBTYDB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  107
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  pyruvic acid 2-thenoylhydrazone 、 二苯基氧化锡 以 乙醇 为溶剂， 以59%的产率得到[Ph2Sn(pyruvic acid thiophene-2-carboxylic hydrazone(-2H))]
  参考文献：
  名称：

  Synthesis, characterization and crystal structures of the organotin(IV) compounds with the Schiff base ligands of pyruvic acid thiophene-2-carboxylic hydrazone and salicylaldehyde thiophene-2-carboxylic hydrazone

  摘要：

  A series of organotin (IV) compounds of the type [R3SnL](2), R is Me (1), Bu (2), [R2SnL](2), R is Ph (3), Me (4), Bu (5), L is pyruvic acid thiophene-2-carboxylic hydrazone, and R2SnL, R is Me (6), Bu (7), Ph (8), L is salicylaldehyde thiophene-2-carboxylic hydrazone have been synthesized in 1:1 molar ratio. All compounds were characterized by elemental analysis, IR, H-1 NMR, C-13 NMR and Sn-119 NMR spectra. The crystal structure of compounds 1, 3, 4, 8 have been determined by X-ray single crystal diffraction analyses, study found that the compounds 1 and 3 are rendered one-dimensional chain structure and the tin atoms are five-coordmated in a distorted trigonal-bipyramidal geometry. The compound 4 has a dimeric structure and the central tin atom is rendered seven-coordinate in a distorted pentagonal-bipyramid configuration. While the compound 8 is a monomer in which the tin atom adopts five-coordinated in distorted trigonal-bipyramidal geometry. Crown Copyright (C) 2006 Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2006.10.038

文献信息

• Synthesis and structural characterization of organotin(IV) compounds derived from the self-assembly of hydrazone Schiff base series and various alkyltin salts
  作者：Min Hong、Han-Dong Yin、Shao-Wen Chen、Da-Qi Wang

  DOI：10.1016/j.jorganchem.2009.11.035

  日期：2010.3

  Reactions of pyruvic acid hydrazone series [pyruvic acid thiophenecarbonyl hydrazone (L1), pyruvic acid 4-hydroxybenzoylhydrazone (L2), pyruvic acid salicyloylhydrazone (L3), pyruvic acid benzoylhydrazone (L4)], or salicylaldehyde hydrazone Schiff base ligand [salicylaldehyde isonicotinoylhydrazone (L5)] with different alkyltin salts result in six new organotin(IV) compounds, (n-Bu)2Sn[2-SC4H3CON

  丙酮酸系列[丙酮酸噻吩羰基（L1），丙酮酸4-羟基苯甲酰hydr（L2），丙酮酸水杨酰hydr（L3），丙酮酸苯甲酰hydr（L4）]或水杨醛缩醛的六种反应新的有机锡（IV）化合物，（n -Bu）2 Sn [2-SC 4 H 3 CON 2 C（CH 3）CO 2 ]（HOC 3 H 7 - i）} 2（1），[（n -Bu）2 SnCl（O）（n -Bu）2 Sn（O）[C 6 H 4 CON 2 C（CH 3）CO 2 ] Sn（n -Bu）2（HOCH 3）} 2 ] ∞（2），（o -ClBz）2 Sn [4- HOC 6 H 4 CON 2 C（CH 3）CO 2 ]（HOC 2 H 5）} 2（3），（n -C 8 H 17）2 Sn [2-HOC 6 H4 CON 2 C（CH 3）CO 2 ]（H 2 O）} 2（4），（Ñ -Bu）2 Sn的[C 6 H ^ 5
• Domiano, Paolo; Mucchino, Claudio; Nardelli, Mario, Gazzetta Chimica Italiana, 1988, vol. 118, # 4, p. 309 - 314
  作者：Domiano, Paolo、Mucchino, Claudio、Nardelli, Mario、Predieri, Giovanni、Pelizzi, Corrado

  DOI：——

  日期：——
• Synthesis, characterization and crystal structures of the organotin(IV) compounds with the Schiff base ligands of pyruvic acid thiophene-2-carboxylic hydrazone and salicylaldehyde thiophene-2-carboxylic hydrazone
  作者：Han Dong Yin、Shao Wen Chen、Lin Wei Li、Da Qi Wang

  DOI：10.1016/j.ica.2006.10.038

  日期：2007.5

  A series of organotin (IV) compounds of the type [R3SnL](2), R is Me (1), Bu (2), [R2SnL](2), R is Ph (3), Me (4), Bu (5), L is pyruvic acid thiophene-2-carboxylic hydrazone, and R2SnL, R is Me (6), Bu (7), Ph (8), L is salicylaldehyde thiophene-2-carboxylic hydrazone have been synthesized in 1:1 molar ratio. All compounds were characterized by elemental analysis, IR, H-1 NMR, C-13 NMR and Sn-119 NMR spectra. The crystal structure of compounds 1, 3, 4, 8 have been determined by X-ray single crystal diffraction analyses, study found that the compounds 1 and 3 are rendered one-dimensional chain structure and the tin atoms are five-coordmated in a distorted trigonal-bipyramidal geometry. The compound 4 has a dimeric structure and the central tin atom is rendered seven-coordinate in a distorted pentagonal-bipyramid configuration. While the compound 8 is a monomer in which the tin atom adopts five-coordinated in distorted trigonal-bipyramidal geometry. Crown Copyright (C) 2006 Published by Elsevier B.V. All rights reserved.