1,3-bis(cyclohexylphosphanyl)propane | 97472-13-4

• 分子结构分类: 有机化合物 - 有机磷化合物
• 英文名称: 1,3-bis(cyclohexylphosphanyl)propane
• 英文别名: 1,3-(dicyclohexylphosphino)propane；Propylen-1.3-bis-monocyclohexylphosphin；Cyclohexyl(3-cyclohexylphosphanylpropyl)phosphane
• CAS: 97472-13-4
• 化学式: C₁₅H₃₀P₂
• 分子量: 272.351
• InChiKey: IFLBDFFXXXCOME-UHFFFAOYSA-N

物化性质

• 沸点：
  391.8±12.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,3-bis(cyclohexylphosphanyl)propane 在 双(三甲基硅烷基)氨基钾 作用下， 以 氘代四氢呋喃 、 二氯甲烷 、 甲苯 为溶剂， 20.0~80.0 ℃ 、33.33 kPa 条件下， 反应 16.42h， 生成
  参考文献：
  名称：

  一氧化碳和氨钯催化芳基氯氨基羰基化的机理研究

  摘要：

  报道了可靠的、钯催化的芳基氯化物与氨的氨基羰基化的机理信息。该反应以乙烯络合物 1 作为催化剂发生，通过分离催化中间体和动力学测量获得了机理信息，包括在 CO 存在下将芳基氯氧化加成钯 (0) 络合物的第一个机理数据。合成和苯酰基卤化钯中间体，并对这些中间体的形成和反应进行动力学测量，以确定在 CO 存在下芳基溴化物和氯化物与 Pd(0) 二羰基化合物的氧化加成机理和氨与 Pd(II) 苯甲酰络合物反应形成苯甲酰胺。芳基氯化物和芳基溴化物的氧化加成被确定发生在卤代芳烃与带有二齿膦和一个 CO 配体的三配位 Pd(0) 物质的限速反应中。初级 13C 动力学同位素效应表明该步骤涉及碳-卤素键的断裂。我们的数据表明，苯酰卤化钯络合物与氨反应形成苯甲酰胺的途径包括用氨将氯化物从苯酰钯氯化物络合物中可逆置换，结合的氨去质子化形成苯酰钯酰氨基络合物，然后还原消除到形成CN键。与该机制一致，芳基钯酰胺络合物与

  DOI：

  10.1021/jacs.8b04073
• 作为产物：
  描述：

  1,3-二溴丙烷 、 环已基膦 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 0.33h， 以100%的产率得到1,3-bis(cyclohexylphosphanyl)propane
  参考文献：
  名称：

  Nickel Bis-Diphosphine Complexes: Controlling the Binding and Heterolysis of H₂

  摘要：

  Two new Ni(II) complexes, the homoleptic [Ni-(8P(2)(Cy)N(H))(2)](2+) complex (8P(2)(Cy)N(H) = 3,7-cyclohexyl-1-atnino-3,7-diphosphacyclooctane) containing two pendant amines on adjacent ligands, and the heteroleptic [Ni(8P(2)(Cy)N(H))center dot(dppe)(2+) complex (dppe = bis(diphenylphosphino)ethane) containing only a single pendant, amine, have been syrithesited, and theii electrochemical properties are reported. The [Ni(8P(2)(Cy)N(H))(dppe)(2+) complex is capable of heterolytically cleaving hydrogen, allowing for the first observation of an endoprotonated nickel hydride related to the [Ni((P2N2R)-N-R')(2)](2+) family of complexes. The [Ni(88P(2)(Cy)N(H))(dppe)](2+) complex did not exhibit electrocatalytic H-2 oxidation activity; however, [Ni(8P(2)(Cy)N(H))(2)](2+) is an active electrocatalyst for H-2 OXidaiOrl with a maximum turnover:frequency (k(obs)) of 18 s(-1) under 1 atm H-2 at E-cat/2 = -0.71 V versus the ferrocenium/ferrocene (Cp2Fe+/0) couple. In addition to an analysis of the effect of the number of pendant amines. on the rates of electrocatalytic H2 oxidation of compounds related to the [Ni((P2N2R)-N-R')(2)](2+) family, the effect of the secondary pendant amine on intermolecular deprotonation is discussed.

  DOI：

  10.1021/acs.organomet.6b00486

文献信息

• PROCESS FOR THE PREPARATION OF PYRIDO [ 2-1-A] ISOQUINOLINE DERIVATIVES BY CATALYTIC ASYMMETRIC HYDROGENATION OF AN ENAMINE
  申请人：Abrecht Stefan

  公开号：US20080076925A1

  公开（公告）日：2008-03-27

  The invention relates to a process for the preparation of pyrido[2,1- a ] isoquinoline derivatives of the formula wherein R 2 , R 3 and R 4 are as defined in the specification, comprising the steps of a) catalytic asymmetric hydrogenation of an enamine of the formula wherein R 1 is lower alkyl, in the presence of a transition metal catalyst containing a chiral diphosphane ligand, b) introduction of an amino protecting group Prot and c) amidation of the ester to form an amide of formula wherein R 2 , R 3 , R 4 and Prot are as defined in the specification.

  本发明涉及一种制备式为的吡啶并[2,1-a]异喹啉衍生物的方法，其中R2、R3和R4如规范中所定义，包括以下步骤：a）在手性二膦配体存在下，对式为的烯胺进行催化不对称氢化，其中R1为低碳基；b）引入氨基保护基Prot；c）酰胺化酯，形成式为的酰胺，其中R2、R3、R4和Prot如规范中所定义。
• BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX
  申请人：Asaumi Taku

  公开号：US20100184978A1

  公开（公告）日：2010-07-22

  A bipyridine compound represented by the formula (1): wherein R 1 , R 2 and R 3 each independently represent a C1-C10 alkyl group which may be substituted etc., and R 4 , R 5 , R 6 , R 7 and R 8 each independently represent a hydrogen atom etc., a transition metal complex obtained by contacting a bipyridine compound represented by the formula (1) with a compound of a transition metal belonging to Group 9, 10 or 11, and a method for production of a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups are bonded to an aromatic ring with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) being structurally different from the above-mentioned aromatic compound (A) and having one or two leaving groups bonded to an aromatic ring, in the presence of the transition metal complex.

  一种以式(1)表示的联吡啶化合物：其中R1、R2和R3各自独立地表示可以被取代的C1-C10烷基等，而R4、R5、R6、R7和R8各自独立地表示氢原子等，通过将式(1)表示的联吡啶化合物与属于9、10或11族过渡金属的化合物接触而获得的过渡金属配合物，以及一种制备共轭芳香化合物的方法，包括在过渡金属配合物的存在下，将一个或两个离去基团与芳环结合的芳香化合物（A）与具有与上述芳香化合物（A）相同结构的芳香化合物（A）或结构不同于上述芳香化合物（A）且具有一个或两个离去基团与芳环结合的芳香化合物（B）反应。
• TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX
  申请人：Asaumi Taku

  公开号：US20110046336A1

  公开（公告）日：2011-02-24

  A transition metal complex obtained by contacting a bipyridine compound represented by the formula (1): wherein R 1 , R 2 and R 3 represent a C1-C10 alkyl group which may be substituted, etc., and R 4 and R 5 represent a hydrogen atom etc., with a compound of a transition metal belonging to Group 9, 10 or 11, and a process for producing a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups are bonded to an aromatic ring with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) being structurally different from the above-mentioned aromatic compound (A) and having one or two leaving groups bonded to an aromatic ring, in the presence of said transition metal complex.

  通过将式（1）所表示的联吡啶化合物与属于9、10或11族的过渡金属化合物接触而获得的过渡金属配合物，其中R1、R2和R3代表C1-C10烷基，可以被取代等，而R4和R5代表氢原子等。制备共轭芳香化合物的方法包括，在所述过渡金属配合物的存在下，将一个芳香化合物（A），其中一个或两个离去基团与芳香环相键合，与具有与上述芳香化合物（A）相同结构的芳香化合物（A）或在结构上不同于上述芳香化合物（A）并且具有一个或两个离去基团与芳香环相键合的芳香化合物（B）反应。
• METHOD FOR PRODUCTION OF CONJUGATED POLYMER
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1997844A1

  公开（公告）日：2008-12-03

  A method for production of a conjugated polymer comprising contacting (A) an aromatic monomer having at least two boron-containing functional groups with an aromatic monomer having at least two reactive functional groups or (B) aromatic monomers having at least one boron-containing functional group and at least one reactive functional group with each other, both in an ether solvent in the presence of a palladium catalyst wherein a phosphine compound is coordinated to palladium, cesium carbonate and 1 to 100 moles of water per 1 mole of the boron-containing functional group of the above-mentioned aromatic monomer.

  一种生产共轭聚合物的方法，包括将(A)具有至少两个含硼官能团的芳香族单体与具有至少两个活性官能团的芳香族单体或(B)具有至少一个含硼官能团和至少一个活性官能团的芳香族单体相互接触、二者均在醚溶剂中，在钯催化剂（其中膦化合物与钯、碳酸铯配位）和每 1 摩尔上述芳香族单体的含硼官能团含有 1 至 100 摩尔水的条件下进行。
• TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2192124A1

  公开（公告）日：2010-06-02

  A transition metal complex obtained by contacting a bipyridine compound represented by the formula (1): wherein R1, R2 and R3 represent a C1-C10 alkyl group which may be substituted, etc., and R4 and R5 represent a hydrogen atom etc., with a compound of a transition metal belonging to Group 9, 10 or 11, and a process for producing a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups are bonded to an aromatic ring with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) being structurally different from the above-mentioned aromatic compound (A) and having one or two leaving groups bonded to an aromatic ring, in the presence of said transition metal complex.

  一种过渡金属配合物，通过与式 (1) 所代表的联吡啶化合物接触而获得： 其中 R1、R2 和 R3 代表可被取代的 C1-C10 烷基等，R4 和 R5 代表氢原子等、一种生产共轭芳香族化合物的工艺，包括在上述过渡金属配合物存在下，将一个或两个离去基团键合在芳香环上的芳香族化合物(A)与结构与上述芳香族化合物(A)相同的芳香族化合物(A)或结构不同于上述芳香族化合物(A)且一个或两个离去基团键合在芳香环上的芳香族化合物(B)反应。