methyl-n-octyldihydroxysilane | 156218-16-5

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: methyl-n-octyldihydroxysilane
• 英文别名: Dihydroxy-methyl-octylsilane
• CAS: 156218-16-5
• 化学式: C₉H₂₂O₂Si
• 分子量: 190.358
• InChiKey: RPBRAWNJMIMKAH-UHFFFAOYSA-N

物化性质

• 沸点：
  268.2±23.0 °C(Predicted)
• 密度：
  0.915±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  methyl-n-octyldihydroxysilane 、 苯硼酸 以 甲苯 为溶剂， 以87%的产率得到2,6-Dimethyl-2,6-dioctyl-4,8-diphenyl-[1,3,5,7,2,6,4,8]tetroxadisiladiborocane
  参考文献：
  名称：

  环-硼三硅氧烷和环-二硼酸酯四硅氧烷衍生物及其与胺的反应：（p -BrC 6 H 4 BO）2（Ph 2 SiO）2的晶体和分子结构

  摘要：

  新的环-diboratetrasiloxanes（RBO）2（R' 2的SiO）2（R = p -BrC 6 ħ 4，ö -MeC 6 ħ 4，米-NH 2 ç 6 ħ 4，米-NO 2 ç 6 ħ 4卜ñ ; R' 2 =苯基2，R =苯基，p -BrC 6 ħ 4，米-NO 2 ç 6 ħ4 ; R' 2 =辛Ñ / Me）中和环-boratrisiloxanes（RBO）（R' 2的SiO）2（R = p -BrC 6 ħ 4，中号-NH 2 ç 6 ħ 4 ; R' 2 =我2中，Ph / Me）通过缩合反应高产率地制备。环为（PhBO）获得：-Diboratetrasiloxane·胺加合物（11）2（PH 2的SiO）2与环己胺，三乙胺，哌啶和异丁胺和（ø -MeC 6H 4 BO）2（Ph 2 SiO）2和吗啉；相反，环-硼三硅氧烷对胺不反应。这些硼硅氧烷环的路易斯酸度是通过

  DOI：

  10.1016/s0022-328x(99)00631-2
• 作为产物：
  描述：

  二氯甲基辛基甲硅烷 在 正丁基锂 、 三氟乙酸 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 2.5h， 生成 methyl-n-octyldihydroxysilane
  参考文献：
  名称：

  Bis(2-thienyl)silanes: new, versatile precursors to arylsilanediols

  摘要：

  Silanediols have been shown to be effective bioisosteres for the hydrated carbonyl group. Current methods for the formation of silanediols place a number of constraints on how and where this functionality may be used. A range of arylsilanes that would allow both the formation of arylsilanediols and that are also compatible with multi-step synthetic routes, have been investigated as possible precursors to silanediols. Through this study bis(2-furyl)silanes and, in particular, bis(2-thienyl)si lanes have been identified as practical precursors to arylsilanediols. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.03.095

文献信息

• cyclo-Boratrisiloxane and cyclo-diboratetrasiloxane derivatives and their reactions with amines: crystal and molecular structure of (p-BrC6H4BO)2(Ph2SiO)2
  作者：Michael A. Beckett、David E. Hibbs、Michael B. Hursthouse、K.M.Abdul Malik、Paul Owen、K.Sukumar Varma

  DOI：10.1016/s0022-328x(99)00631-2

  日期：2000.2

  new cyclo-diboratetrasiloxanes (RBO)2(R′2SiO)2 (R=p-BrC6H4, o-MeC6H4, m-NH2C6H4, m-NO2C6H4, Bun; R′2=Ph2, R=Ph, p-BrC6H4, m-NO2C6H4; R′2=octn/Me) and cyclo-boratrisiloxanes (RBO)(R′2SiO)2 (R=p-BrC6H4, m-NH2C6H4; R′2=Me2, Ph/Me) were prepared in high yield by condensation reactions. cyclo-Diboratetrasiloxane·amine adducts (1:1) were obtained for (PhBO)2(Ph2SiO)2 with cyclohexylamine, triethylamine,

  新的环-diboratetrasiloxanes（RBO）2（R' 2的SiO）2（R = p -BrC 6 ħ 4，ö -MeC 6 ħ 4，米-NH 2 ç 6 ħ 4，米-NO 2 ç 6 ħ 4卜ñ ; R' 2 =苯基2，R =苯基，p -BrC 6 ħ 4，米-NO 2 ç 6 ħ4 ; R' 2 =辛Ñ / Me）中和环-boratrisiloxanes（RBO）（R' 2的SiO）2（R = p -BrC 6 ħ 4，中号-NH 2 ç 6 ħ 4 ; R' 2 =我2中，Ph / Me）通过缩合反应高产率地制备。环为（PhBO）获得：-Diboratetrasiloxane·胺加合物（11）2（PH 2的SiO）2与环己胺，三乙胺，哌啶和异丁胺和（ø -MeC 6H 4 BO）2（Ph 2 SiO）2和吗啉；相反，环-硼三硅氧烷对胺不反应。这些硼硅氧烷环的路易斯酸度是通过
• Bis(2-thienyl)silanes: new, versatile precursors to arylsilanediols
  作者：Thomas F. Anderson、Matthew A.J. Statham、Michael A. Carroll

  DOI：10.1016/j.tetlet.2006.03.095

  日期：2006.5

  Silanediols have been shown to be effective bioisosteres for the hydrated carbonyl group. Current methods for the formation of silanediols place a number of constraints on how and where this functionality may be used. A range of arylsilanes that would allow both the formation of arylsilanediols and that are also compatible with multi-step synthetic routes, have been investigated as possible precursors to silanediols. Through this study bis(2-furyl)silanes and, in particular, bis(2-thienyl)si lanes have been identified as practical precursors to arylsilanediols. (c) 2006 Elsevier Ltd. All rights reserved.