2-甲基-N-(5-氧代-1-苯基-4H-吡唑-3-基)丙-2-烯酰胺 | 3331-54-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑啉类
• 中文名称: 2-甲基-N-(5-氧代-1-苯基-4H-吡唑-3-基)丙-2-烯酰胺
• 英文名称: 1-Phenyl-3-methacrylamido-5-pyrazolon
• 英文别名: 1-Phenyl-3-(methacryloylamino)-2-pyrazolin-5-on；2-methyl-N-(5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl)-acrylamide；N-(4,5-dihydro-5-oxo-1-phenyl-1H-pyrazol-3-yl)methacrylamide；2-methyl-N-(5-oxo-1-phenyl-4H-pyrazol-3-yl)prop-2-enamide
• CAS: 3331-54-2
• 化学式: C₁₃H₁₃N₃O₂
• 分子量: 243.265
• InChiKey: MXLQAWXKAKUDHC-UHFFFAOYSA-N

物化性质

• 熔点：
  170-172 °C
• 密度：
  1.22±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  61.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Copolymer latex and photographic silver halide materials containing such latex
  申请人：AGFA-GEVAERT naamloze vennootschap

  公开号：EP0027284A1

  公开（公告）日：1981-04-22

  Latexes suited for homogeneously incorporating compounds with a photographically useful group into photographic silver halide emulsion materials. The latex incorporates a copolymer comprising recurring units of a monomer with photographically useful group, and recurring units of surface active monomer, according to the general formula : wherein: R' is hydrogen or methyl, n is0or1to20, L is R2 is hydrogen or a hydrocarbon group, R3 is a monovalent chemical bond or a bivalent aliphatic hydrocarbon group or such group interrupted by the group -COO- or-CONR-, and Y is a sulpho, sulphato or phosphono group in acid or salt form, and at least one of the groups -(CH2)n-, R2 or R3 is or comprises a hydrocarbon chain of at least 8 C-atoms.

  适用于在照相卤化银乳剂材料中均匀加入具有照相用途基团的化合物的胶乳。这种胶乳包含一种共聚物，该共聚物由具有摄影用途基团的单体的重复单元和表面活性单体的重复单元组成，其通式为 ： 其中 R' 是氢或甲基、 n 为 0 或 1 至 20、 L 是 R2 是氢或烃基、 R3 是一价化学键或二价脂肪族烃基或被基团-COO-或-CONR-打断的此类基团，以及 Y 是酸或盐形式的硫代、硫酸根或磷酰基，且基团-(CH2)n-、R2 或 R3 中至少有一个是或包含至少 8 个 C 原子的烃链。
• New method for the detection of specific binding agents and their corresponding bindable substances
  申请人：JANSSEN PHARMACEUTICA N.V.

  公开号：EP0227173A2

  公开（公告）日：1987-07-01

  A method of qualitatively or quantitatively determining a component of a complex formed between at least one specific binding agent and its corresponding bindable substance. Said method comprises labelling at least one component of said complex with a marker which is easier to determine than the complex itself, whereby the marker used consists of latex particles which can be detected visually either by colour or fluorescence. Preferably the marker consists of coloured or colourable latex particles and the determination is based on the colour characteristics of the latex particles as such or, in the instance that colourable latex particles are used, on the colour characteristics of the coloured particles derived therefrom. The colour, respectively fluorescence signal is, if necessary after development, easily detected and optionally quantified. The invention further comprises coloured or colourable latex particles coated with specific binding proteins and test kits containing the same.

  一种定性或定量测定至少一种特异性结合剂与其相应的可结合物质之间形成的复合物的组分的方法。该方法包括用一种比复合物本身更容易确定的标记物对复合物中的至少一种成分进行标记，其中使用的标记物由可通过颜色或荧光目测的乳胶颗粒组成。标记物最好由有色或有色胶乳颗粒组成，根据胶乳颗粒本身的颜色特征来确定，或者在使用有色胶乳颗粒的情况下，根据由此产生的有色颗粒的颜色特征来确定。如有必要，可在显影后对颜色和荧光信号进行检测和量化。本发明还包括涂有特异性结合蛋白的有色或有色胶乳颗粒以及含有这些颗粒的检测试剂盒。
• US4128427A
  申请人：——

  公开号：US4128427A

  公开（公告）日：1978-12-05
• US4340664A
  申请人：——

  公开号：US4340664A

  公开（公告）日：1982-07-20
• US4388404A
  申请人：——

  公开号：US4388404A

  公开（公告）日：1983-06-14