2-methoxy-1-[2-methyl-4-tri(propan-2-yl)silyloxycyclohex-3-en-1-yl]ethanone | 134745-48-5

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 2-methoxy-1-[2-methyl-4-tri(propan-2-yl)silyloxycyclohex-3-en-1-yl]ethanone
• CAS: 134745-48-5
• 化学式: C₁₉H₃₆O₃Si
• 分子量: 340.579
• InChiKey: MSYOMUZDXSCSHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.32
• 重原子数：
  23.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  氨基邻苯二甲胺 、 2-methoxy-1-[2-methyl-4-tri(propan-2-yl)silyloxycyclohex-3-en-1-yl]ethanone 在 臭氧 作用下， 生成 tri(propan-2-yl)silyl 3-[1-(1,3-dioxoisoindol-2-yl)-2-(methoxymethyl)-4-methylpyrrol-3-yl]propanoate
  参考文献：
  名称：

  2-oxo-3-butenoate esters as dienophiles and their utility in a novel synthesis of pyrroles

  摘要：

  Trisubstituted pyrroles of type 8 have been prepared in a regiospecific fashion by a two step sequence involving Diels-Alder reaction of 2-oxo-3-butenoate esters 1 with 2-alkoxy-1,3-pentiadiene derivatives 13, followed by ozonolysis and Paal-Knorr cyclization.

  DOI：

  10.1016/s0040-4039(00)74324-3
• 作为产物：
  描述：

  1-甲氧基丁-3-烯-2-酮 、 (E)-triisopropyl(penta-1,3-dien-2-yloxy)silane 以 苯 为溶剂， 以63%的产率得到2-methoxy-1-[2-methyl-4-tri(propan-2-yl)silyloxycyclohex-3-en-1-yl]ethanone
  参考文献：
  名称：

  2-oxo-3-butenoate esters as dienophiles and their utility in a novel synthesis of pyrroles

  摘要：

  Trisubstituted pyrroles of type 8 have been prepared in a regiospecific fashion by a two step sequence involving Diels-Alder reaction of 2-oxo-3-butenoate esters 1 with 2-alkoxy-1,3-pentiadiene derivatives 13, followed by ozonolysis and Paal-Knorr cyclization.

  DOI：

  10.1016/s0040-4039(00)74324-3

文献信息

• 2-oxo-3-butenoate esters as dienophiles and their utility in a novel synthesis of pyrroles
  作者：Peter A. Jacobi、Guolin Cai

  DOI：10.1016/s0040-4039(00)74324-3

  日期：1991.4

  Trisubstituted pyrroles of type 8 have been prepared in a regiospecific fashion by a two step sequence involving Diels-Alder reaction of 2-oxo-3-butenoate esters 1 with 2-alkoxy-1,3-pentiadiene derivatives 13, followed by ozonolysis and Paal-Knorr cyclization.
• Jacobi, Peter A.; Cai, Guolin, Heterocycles, 1993, vol. 35, # 2, p. 1103 - 1120
  作者：Jacobi, Peter A.、Cai, Guolin

  DOI：——

  日期：——