[(Me3Si)2CH]2GeI[(CH2)(CH3)N(CH2)N(CH3)2)] | 1148128-60-2

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: [(Me3Si)2CH]2GeI[(CH2)(CH3)N(CH2)N(CH3)2)]
• 英文别名: N'-[[bis[bis(trimethylsilyl)methyl]-iodogermyl]methyl]-N,N,N'-trimethylmethanediamine
• CAS: 1148128-60-2
• 化学式: C₁₉H₅₁GeIN₂Si₄
• 分子量: 619.464
• InChiKey: YDWKAEWXNLLSIC-UHFFFAOYSA-N

物化性质

• 沸点：
  450.5±55.0 °C(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.61
• 重原子数：
  27
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  碘苯 、 四甲基甲烷二胺 、 bis[bis(trimethylsilyl)methyl]germanium(II) 以 neat (no solvent) 为溶剂， 以95%的产率得到[(Me3Si)2CH]2GeI[(CH2)(CH3)N(CH2)N(CH3)2)]
  参考文献：
  名称：

  Silylene- and Germylene-Mediated C−H Activation: Reaction with Alkanes, Ethers, and Amines

  摘要：

  The reaction of silylene Si[N-2(Bu-t)(2)C2H2] and Ph-X (X = I, Br) in alkane and ethereal solvents results in the formation of C-H activation product [C2H2(Bu-t(2))N-2]SiRI and an equivalent of benzene or oxidative-addition product [C2H2(Bu-t(2))N-2]SiRI . The ratio of products obtained is dependent upon substrate and concentration. This class of reaction has been extended for Si[N-2(Bu-t)(2)C2H2] and Ge[CH(SiMe3)(2)](2) to alkylamines. The primary kinetic isotope effect has been measured for the reaction of Si[N-2(Bu-t)(2)C2H2] with Et2O and determined to be k(H)/k(D) = 5.1 +/- 0.1. The reaction of Ge[CH(SiMe3)(2)](2) and Ph-Br with THF was determined to be second order. A large isotope effect ranging from 1.8 to 1.1 was measured for a variety of deuterated aryl halides, consistent with an initial electron transfer to the aryl halide.

  DOI：

  10.1021/om900182z

文献信息

• Silylene- and Germylene-Mediated C−H Activation: Reaction with Alkanes, Ethers, and Amines
  作者：Randon H. Walker、Karla A. Miller、Sara L. Scott、Zuzanna T. Cygan、Jeffrey M. Bartolin、Jeff W. Kampf、Mark M. Banaszak Holl

  DOI：10.1021/om900182z

  日期：2009.5.11

  The reaction of silylene Si[N-2(Bu-t)(2)C2H2] and Ph-X (X = I, Br) in alkane and ethereal solvents results in the formation of C-H activation product [C2H2(Bu-t(2))N-2]SiRI and an equivalent of benzene or oxidative-addition product [C2H2(Bu-t(2))N-2]SiRI . The ratio of products obtained is dependent upon substrate and concentration. This class of reaction has been extended for Si[N-2(Bu-t)(2)C2H2] and Ge[CH(SiMe3)(2)](2) to alkylamines. The primary kinetic isotope effect has been measured for the reaction of Si[N-2(Bu-t)(2)C2H2] with Et2O and determined to be k(H)/k(D) = 5.1 +/- 0.1. The reaction of Ge[CH(SiMe3)(2)](2) and Ph-Br with THF was determined to be second order. A large isotope effect ranging from 1.8 to 1.1 was measured for a variety of deuterated aryl halides, consistent with an initial electron transfer to the aryl halide.