1-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yloxy)-2,3-epoxypropane | 165118-13-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yloxy)-2,3-epoxypropane
• 英文别名: 1-Cyclohexyloxy-2,2,6,6-tetramethyl-4-(2,3-epoxypropoxy)piperidine；4-(2,3-epoxypropoxy)-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine；1-cyclohexyloxy-2,2,6,6-tetramethyl-4-(oxiran-2-ylmethoxy)piperidine
• CAS: 165118-13-8
• 化学式: C₁₈H₃₃NO₃
• 分子量: 311.465
• InChiKey: VWVQFWXIEKWPLR-UHFFFAOYSA-N

物化性质

• 沸点：
  387.5±52.0 °C(Predicted)
• 密度：
  1.05±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  34.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yloxy)-2,3-epoxypropane 、 4-羟基苯乙烯 生成 4-(3-[4-Vinylphenoxy]-2-hydroxypropoxy)-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine
  参考文献：
  名称：

  Adducts of hindered amine-epoxides as stabilizers

  摘要：

  式I或II的酯或苯醚，其中m和n均为1至6的整数；A.sup.1是具有1至30个碳原子的m价碳氢基团；或者是具有2至30个碳原子的m价碳氢基团，其中包含氧、氮和/或硫的杂原子，其自由价位于碳原子上，在m=2的情况下，A.sup.1还是直接键；A.sup.2是具有6至30个碳原子的n价芳香或芳基碳氢基团；或者是具有5至30个碳原子的n价芳香或芳基碳氢基团，其中包含氧、氮和/或硫的杂原子，n个自由价位于芳香环的碳原子上；R.sup.1是氢；具有1至36个碳原子的碳氢基团或碳氢氧基基团，未经取代或通过--CO--N(R.sup.3).sub.2取代或通过--CO--N(R.sup.3)--或--N(R.sup.3)--CO--中断或具有1至6个氧或硫原子；苯甲酰或萘甲酰，每个都被1至3个C.sub.1-C.sub.4烷基或C.sub.1-C.sub.4烷氧基基团取代；或--CO--R.sup.2；其中R.sup.2是C.sub.1-C.sub.18烷基；C.sub.5-C.sub.8环烷基；苯基；萘基；C.sub.7-C.sub.9苯基烷基；或C.sub.11-C.sub.14萘基烷基；R.sup.3具有与R.sup.2相同的含义或是氢。这些化合物适用于稳定有机材料，以抵抗光、氧和/或热的有害影响。

  公开号：

  US05665885A1
• 作为产物：
  描述：

  1-环己氧基-2,2,6,6-四甲基哌啶-4-醇 、 环氧氯丙烷 在 sodium hydroxide 、 四丁基溴化铵 作用下， 以 ice-water 、 水 、 甲苯 为溶剂， 生成 1-(1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-yloxy)-2,3-epoxypropane
  参考文献：
  名称：

  Tetraalkyl-4-(2,3-epoxypropoxy) piperidine compounds as stabilizers

  摘要：

  公式I或II的酯类或苯醚如下所示：其中m和n均为1到6范围内的整数；A.sup.1是具有1到30个碳原子的m价碳氢基团；或者是具有2到30个碳原子的m价碳氢基团，其中含有氧、氮和/或硫杂原子，其自由度位于碳原子上；在m=2的情况下，A.sup.1还是一个直接键；A.sup.2是具有6到30个碳原子的n价芳香或芳基碳氢基团；或者是具有5到30个碳原子的n价芳香或芳基碳氢基团，其中含有氧、氮和/或硫杂原子，n个自由度位于构成芳香环的碳原子上；R.sup.1是氢；具有1到36个碳原子的未取代或取代的烃基或烃氧基基团，可被--CO--N(R.sup.3).sub.2取代或中断--CO--N(R.sup.3)--或--N(R.sup.3)--CO--或1到6个氧或硫原子；苯甲酰基或萘甲酰基，每个都被1到3个C.sub.1 -C.sub.4烷基或C.sub.1 -C.sub.4烷氧基基团取代；或者--CO--R.sup.2；其中R.sup.2是C.sub.1 -C.sub.18烷基；C.sub.5 -C.sub.8环烷基；苯基；萘基；C.sub.7 -C.sub.9苯基烷基；或C.sub.11 -C.sub.14萘基烷基；而R.sup.3具有与R.sup.2相同的含义或者是氢。这些化合物适用于稳定有机材料，抵抗光线、氧气和/或热的有害影响。

  公开号：

  US05457204A1

文献信息

• Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer
  申请人：Ciba-Geigy Corporation

  公开号：US05286865A1

  公开（公告）日：1994-02-15

  1-Hydrocarbyloxy substituted hindered amine compounds which also contain a reactive functional group such as hydroxy, amino, oxirane or carboxyl can be chemically attached to selected polymer substrates by condensation reactions to give polymers containing a chemically-bonded, non-migrating stabilizer having excellent stabilization efficacy for protecting said polymer substrate from the adverse effects of actinic light.

  1-羟基烷氧基取代的受阻胺化合物，还含有反应性官能团，如羟基、氨基、环氧乙烷或羧基，可以通过缩聚反应与选定的聚合物基质化学结合，从而形成含有化学键结合、不迁移的稳定剂的聚合物，该稳定剂对保护所述聚合物基质免受光化学作用的不利影响具有出色的稳定效果。
• Adducts of hindered amine-epoxides as stabilizers
  申请人：Ciba-Geigy Corporation

  公开号：US05665885A1

  公开（公告）日：1997-09-09

  Esters or phenol ethers of the formula I or II ##STR1## in which m and n are each an integer from the range from 1 to 6; A.sup.1 is an m-valent hydrocarbon radical having 1 to 30 carbon atoms; or an m-valent hydrocarbon radical having 2 to 30 carbon atoms, which contains the heteroatoms oxygen, nitrogen and/or sulfur and the free valencies of which are located on carbon atoms and in which A.sup.1, in the case where m=2, additionally is a direct bond; A.sup.2 is an n-valent aromatic or araliphatic hydrocarbon radical having 6 to 30 carbon atoms; or an n-valent aromatic or araliphatic hydrocarbon radical having 5 to 30 carbon atoms, which contains the heteroatoms oxygen, nitrogen and/or sulfur and n free valencies of which are located on those carbon atoms which are a constituent of aromatic rings; R.sup.1 is hydrogen; a hydrocarbon or hydrocarbonoxy radical having 1 to 36 carbon atoms, which is unsubstituted or substituted by --CO--N(R.sup.3).sub.2 or interrupted by --CO--N(R.sup.3)-- or --N(R.sup.3)--CO-- or 1 to 6 oxygen or sulfur atoms; benzoyl or naphthoyl, each of which is substituted by 1 to 3 C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy radicals; or --CO--R.sup.2 ; in which R.sup.2 is C.sub.1 -C.sub.18 alkyl; C.sub.5 -C.sub.8 cycloalkyl; phenyl; naphthyl; C.sub.7 -C.sub.9 phenylalkyl; or C.sub.11 -C.sub.14 naphthylalkyl; and R.sup.3 has the same meanings as R.sup.2 or is hydrogen, are described. The compounds are suitable for stabilizing organic material against the damaging influence of light, oxygen and/or heat.

  式I或II的酯或苯醚，其中m和n均为1至6的整数；A.sup.1是具有1至30个碳原子的m价碳氢基团；或者是具有2至30个碳原子的m价碳氢基团，其中包含氧、氮和/或硫的杂原子，其自由价位于碳原子上，在m=2的情况下，A.sup.1还是直接键；A.sup.2是具有6至30个碳原子的n价芳香或芳基碳氢基团；或者是具有5至30个碳原子的n价芳香或芳基碳氢基团，其中包含氧、氮和/或硫的杂原子，n个自由价位于芳香环的碳原子上；R.sup.1是氢；具有1至36个碳原子的碳氢基团或碳氢氧基基团，未经取代或通过--CO--N(R.sup.3).sub.2取代或通过--CO--N(R.sup.3)--或--N(R.sup.3)--CO--中断或具有1至6个氧或硫原子；苯甲酰或萘甲酰，每个都被1至3个C.sub.1-C.sub.4烷基或C.sub.1-C.sub.4烷氧基基团取代；或--CO--R.sup.2；其中R.sup.2是C.sub.1-C.sub.18烷基；C.sub.5-C.sub.8环烷基；苯基；萘基；C.sub.7-C.sub.9苯基烷基；或C.sub.11-C.sub.14萘基烷基；R.sup.3具有与R.sup.2相同的含义或是氢。这些化合物适用于稳定有机材料，以抵抗光、氧和/或热的有害影响。
• Polyethers containing hindered amine side chains as stabilizers
  申请人：Ciba-Geigy Corporation

  公开号：US05521282A1

  公开（公告）日：1996-05-28

  The invention relates to polyethers of the formula I ##STR1## in which m is 0 or 1; n is an integer in the range from 3 to 100; R.sup.1, in the case where m is 0 or 1, is C.sub.1 -C.sub.36 alkyl or C.sub.7 -C.sub.36 aralkyl, each of which is unsubstituted or substituted by C.sub.5 -C.sub.8 cycloalkyl, is interrupted in the aliphatic part by C.sub.5 -C.sub.8 cycloalkylene or by oxygen or sulfur or --NR.sup.11 -- or is substituted in the aromatic part by 1 to 3 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals; C.sub.3 -C.sub.36 alkenyl; C.sub.5 -C.sub.12 cycloalkyl which is unsubstituted or substituted by 1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals; C.sub.6 -C.sub.10 aryl which is unsubstituted or substituted by 1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub. alkoxy radicals; and R.sup.1, in the case where m is 0, can alternatively be hydrogen; C.sub.1 -C.sub.36 alkoxy or C.sub.7 -C.sub. 36 aralkoxy, each of which is unsubstituted or substituted by C.sub.5 -C.sub.8 cycloalkyl, interrupted in the aliphatic part by C.sub.5 -C.sub.8 cycloalkylene or by oxygen or sulfur or --NR.sup.11 -- or is substituted in the aromatic part by 1 to 3 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals; C.sub.3 -C.sub.36 alkenyloxy; C.sub.5 -C.sub.12 cycloalkoxy which is unsubstituted or substituted by 1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals; or C.sub.6 -C.sub.10 aryloxy which is unsubstituted or substituted by 1 to 4 C.sub.1 -C.sub.4 alkyl and/or C.sub.1 -C.sub.4 alkoxy radicals; R.sup.11 is C.sub.1 -C.sub.18 alkyl, C.sub.5 -C.sub.8 cycloalkyl, phenyl or C.sub.7 -C.sub.9 phenylalkyl; and X is an oxygen or sulfur atom.

  本发明涉及公式I的聚醚，其中m为0或1；n为3至100的整数；R1在m为0或1的情况下为C1-C36烷基或C7-C36芳基烷基，每个烷基或芳基烷基未被取代或被C5-C8环烷基取代，或在脂肪部分中被C5-C8环烷基烷基、氧或硫或--NR11--中断，或在芳香部分中被1至3个C1-C4烷基和/或C1-C4烷氧基取代；C3-C36烯基；C5-C12环烷基，未被取代或被1至4个C1-C4烷基和/或C1-C4烷氧基取代；未被取代或被1至4个C1-C4烷基和/或C1-C4烷氧基取代的C6-C10芳基；在m为0的情况下，R1可以是氢；C1-C36烷氧基或C7-C36芳基烷氧基，每个烷氧基或芳基烷氧基未被取代或被C5-C8环烷基取代，或在脂肪部分中被C5-C8环烷基烷基、氧或硫或--NR11--中断，或在芳香部分中被1至3个C1-C4烷基和/或C1-C4烷氧基取代；C3-C36烯氧基；C5-C12环烷氧基，未被取代或被1至4个C1-C4烷基和/或C1-C4烷氧基取代；未被取代或被1至4个C1-C4烷基和/或C1-C4烷氧基取代的C6-C10芳氧基；R11为C1-C18烷基、C5-C8环烷基、苯基或C7-C9苯基烷基；X为氧或硫原子。
• Polymeric substrates stabilized with N-substituted hindered amines
  申请人：CIBA-GEIGY AG

  公开号：EP0365481A1

  公开（公告）日：1990-04-25

  Hindered amines based on various 2,2,6,6-tetralkylated nitrogen-containing heterocyclic moieties wherein the hindered nitrogen atom on the ring is substituted with OR₁ substituents and the 4-position of the ring is substituted with OR₂ substituents are effective in protecting a variety ofpolymeric substrates against the adverse effects of light, heat and oxygen.

  基于各种 2,2,6,6-四烷基化含氮杂环分子的受阻胺，其中环上的受阻氮原子被 OR₁ 取代基取代，环的 4 位被 OR₂ 取代基取代，可有效保护各种聚合物基材免受光、热和氧的不利影响。
• Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers
  申请人：CIBA-GEIGY AG

  公开号：EP0389419A1

  公开（公告）日：1990-09-26

  1-Hydrocarbyloxy substituted hindered amine compounds which also contain a reactive functional group such as hydroxy, amino, oxirane or carboxyl can be chemically attached to selected polymer substrates by condensation reactions to give polymers containing a chemically-bonded, non-migrating stabilizer having excellent stabilization efficacy for protecting said polymer substrate from the adverse effects of actinic light.

  1-Hydrocarbyloxy 取代的受阻胺化合物还含有羟基、氨基、环氧乙烷或羧基等活性官能团，可通过缩合反应与选定的聚合物基材发生化学键合，从而得到含有化学键合的非迁移稳定剂的聚合物，该稳定剂具有优异的稳定效果，可保护所述聚合物基材免受光辐射的不利影响。