6-[4-[[(2R,3S,4S,5R,6R)-3-hydroxy-6-methoxy-4,5-bis(phenylmethoxy)oxan-2-yl]methoxymethyl]phenoxy]hexanoic acid | 464177-66-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 糖脂
• 英文名称: 6-[4-[[(2R,3S,4S,5R,6R)-3-hydroxy-6-methoxy-4,5-bis(phenylmethoxy)oxan-2-yl]methoxymethyl]phenoxy]hexanoic acid
• CAS: 464177-66-0
• 化学式: C₃₄H₄₂O₉
• 分子量: 594.702
• InChiKey: YTWGXLSKVYYBIJ-SSWJQGRHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  43
• 可旋转键数：
  18
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  113
• 氢给体数：
  2
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  乙基-2,3,4,6-O-四苄基-Beta-D-硫代半乳糖苷 、 Succinic acid mono-((2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-5-hydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl) ester 、 6-[4-[[(2R,3S,4S,5R,6R)-3-hydroxy-6-methoxy-4,5-bis(phenylmethoxy)oxan-2-yl]methoxymethyl]phenoxy]hexanoic acid 、 Pentanedioic acid mono-{4-[(2R,3S,4S,5R,6R)-3,5-bis-benzyloxy-6-methoxy-4-(4-methoxy-benzyloxy)-tetrahydro-pyran-2-ylmethoxymethyl]-phenyl} ester 生成 [(2R,3S,4S,5R,6R)-3,4-Bis-benzyloxy-6-methoxy-5-((3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yl]-methanol
  参考文献：
  名称：

  Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support

  摘要：

  A new method for demixing libraries of compounds that are attached to a soluble polymeric support by tagging starting materials with selective cleavable linkers is described. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00851-1
• 作为产物：
  描述：

  4-allyloxybenzyl chloride 在 sodium hydroxide 、 四(三苯基膦)钯 、 四丁基碘化铵 、 二丁基二甲氧基锡 、 caesium carbonate 作用下， 以 甲醇 、 乙醇 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 生成 6-[4-[[(2R,3S,4S,5R,6R)-3-hydroxy-6-methoxy-4,5-bis(phenylmethoxy)oxan-2-yl]methoxymethyl]phenoxy]hexanoic acid
  参考文献：
  名称：

  Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support

  摘要：

  A new method for demixing libraries of compounds that are attached to a soluble polymeric support by tagging starting materials with selective cleavable linkers is described. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00851-1

文献信息

• Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support
  作者：Galal A. Elsayed、Tong Zhu、Geert-Jan Boons

  DOI：10.1016/s0040-4039(02)00851-1

  日期：2002.5

  A new method for demixing libraries of compounds that are attached to a soluble polymeric support by tagging starting materials with selective cleavable linkers is described. (C) 2002 Elsevier Science Ltd. All rights reserved.