1-(4-nitrobenzoyl)-3-(4-phenylazophenyl)thiourea | 875195-25-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: 1-(4-nitrobenzoyl)-3-(4-phenylazophenyl)thiourea
• 英文别名: Benzamide, 4-nitro-N-[[[4-(2-phenyldiazenyl)phenyl]amino]thioxomethyl]-；4-nitro-N-[(4-phenyldiazenylphenyl)carbamothioyl]benzamide
• CAS: 875195-25-8
• 化学式: C₂₀H₁₅N₅O₃S
• 分子量: 405.437
• InChiKey: QWVXHUMVAVZRBK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  144
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  对氮蒽蓝 、 对硝基苯甲酰异硫氰酸盐 在 盐酸 作用下， 以 丙酮 为溶剂， 反应 2.0h， 生成 1-(4-nitrobenzoyl)-3-(4-phenylazophenyl)thiourea
  参考文献：
  名称：

  Naked eye sensing of anions using thiourea based chemosensors with real time application

  摘要：

  Novel chromogenic sensors with thiourea moiety as receptor unit were synthesized and characterized using IR and NMR spectroscopic techniques. The receptors 1 and 2 bearing hydrogen bonding site demonstrate visually striking color change, UV-vis, and fluorescence responses for F-, AcO-, and OH- over other anions such as Cl-, Br-, H2PO4- and HSO4-. Both the receptors 1 and 2 demonstrate detection limit at micro molar level. Further insight to the nature of interaction between receptors and anions was studied using H-1 NMR titration experiment. In particular, the fluoride of tooth paste and mouthwash in water phase can be detected by receptor 2. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.08.005