2-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-5,5-dimethyl-1,3,2-dioxaphosphorinane | 133586-28-4

• 分子结构分类: 有机化合物 - 有机磷化合物 - 亚磷酸三烷基酯
• 英文名称: 2-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-5,5-dimethyl-1,3,2-dioxaphosphorinane
• 英文别名: 2-(1,1,1,3,3,3-hexafluoro-2-propoxy)-5,5-dimethyl-1,3,2-dioxaphosphorinane；5,5-dimethyl-2-hexafluoroisopropoxy-1,3,2-dioxaphosphorinane；2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-5,5-dimethyl-1,3,2-dioxaphosphinane
• CAS: 133586-28-4
• 化学式: C₈H₁₁F₆O₃P
• 分子量: 300.138
• InChiKey: XXDWOTKLHRQRRE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  2-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-5,5-dimethyl-1,3,2-dioxaphosphorinane 在 sulfur 作用下， 以 1,4-二氧六环 为溶剂， 反应 10.0h， 以48%的产率得到2-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-5,5-dimethyl-1,3,2λ⁵-dioxaphosphorinane 2-sulfide
  参考文献：
  名称：

  摘要：

  2-Polyfluoroalkoxy-1,3,2-dioxaphosphorinanes and related phosphocyclic compounds were prepared by alcoholysis of 2-amino-1,3,2-dioxaphosphorinanes with polyfluorinated alcohols. Principal chemical properties of the products were studied. For the first time copper complexes of fluorine-containing normal phosphites were prepared. A difference in the ligation of copper with fluorinated and nonfluorinated phosphites was shown.

  DOI：

  10.1023/a:1012362630312
• 作为产物：
  描述：

  六氟异丙醇 、 2-diethylamino-5,5-dimethyl-1,3,2-dioxaphosphorinane 以 苯 为溶剂， 反应 48.0h， 以57%的产率得到2-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-5,5-dimethyl-1,3,2-dioxaphosphorinane
  参考文献：
  名称：

  摘要：

  2-Polyfluoroalkoxy-1,3,2-dioxaphosphorinanes and related phosphocyclic compounds were prepared by alcoholysis of 2-amino-1,3,2-dioxaphosphorinanes with polyfluorinated alcohols. Principal chemical properties of the products were studied. For the first time copper complexes of fluorine-containing normal phosphites were prepared. A difference in the ligation of copper with fluorinated and nonfluorinated phosphites was shown.

  DOI：

  10.1023/a:1012362630312

文献信息

• Preparation of Hexacoordinated Tris(bidentate) Phosphorus Compounds with 1,3,2-Dioxaphosphorinane Rings. NMR and X-ray Crystallographic Studies of Their Conformation
  作者：Aleksandra Skowrońska、Jacek Kowara、Rafał Kamiński、Grzegorz Bujacz、Michał W. Wieczorek

  DOI：10.1021/jo990921w

  日期：2000.1.1

  tris(bidentate) hexacoordinated phosphorus compounds 1 with 1,3,2-dioxaphosphorinane rings was prepared and studied by NMR and X-ray crystallography. The X-ray crystal structures showed that the 1,3,2-dioxaphosphorinane ring adopts different conformations depending on the number and size of substituents at the carbon atom C14. Substituents are deployed around the phosphorus atom in a slightly deformed

  制备了一系列新的具有1,3,2-二氧杂磷烷基环的不稳定的三（双）六配位磷化合物1，并通过NMR和X射线晶体学研究。X射线晶体结构表明，1,3,2-二氧杂膦烷基环具有不同的构型，这取决于碳原子C14上取代基的数量和大小。取代基以略微变形的八面体结构分布在磷原子周围。磷原子周围键长的偏差取决于键的特性和负电荷的分布。（1）H和（13）C NMR测量表明，在溶液中1,3,2-二氧杂磷烷基环的柔韧性取决于碳C14上取代基的大小。
• Simultaneous Formation of Cage and Spirane Pentaalkoxyphosphoranes in Reaction of 5,5-Dimethyl-2-(2-oxo-1,2-diphenylethoxy)-1,3,2-dioxaphosphorinane with Hexafluoroacetone
  作者：V. F. Mironov、M. N. Dimukhametov、Ya. S. Blinova、F. Kh. Karataeva

  DOI：10.1134/s1070363220110109

  日期：2020.11
• US7423168B2
  申请人：——

  公开号：US7423168B2

  公开（公告）日：2008-09-09
• ——
  作者：T. S. Kukhareva、L. K. Vasyanina、M. Yu. Antipin、K. A. Lysenko、E. E. Nifant'ev、N. O. Soboleva

  DOI：10.1023/a:1012362630312

  日期：——

  2-Polyfluoroalkoxy-1,3,2-dioxaphosphorinanes and related phosphocyclic compounds were prepared by alcoholysis of 2-amino-1,3,2-dioxaphosphorinanes with polyfluorinated alcohols. Principal chemical properties of the products were studied. For the first time copper complexes of fluorine-containing normal phosphites were prepared. A difference in the ligation of copper with fluorinated and nonfluorinated phosphites was shown.