3-(4-氯苄基)哌啶 | 136422-52-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 3-(4-氯苄基)哌啶
• 英文名称: 3-(4-Chlorobenzyl)-piperidine
• 英文别名: 3-[(4-chlorophenyl)methyl]piperidine
• CAS: 136422-52-1
• 化学式: C₁₂H₁₆ClN
• mdl: MFCD07383554
• 分子量: 209.71
• InChiKey: VEVHEHZAQHSNBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS
  申请人：Biogen MA Inc.

  公开号：EP3765458A1

  公开（公告）日：2021-01-20
• [EN] 3- OR 4-SUBSTITUTED PIPERIDINE COMPOUNDS<br/>[FR] COMPOSÉS DE PIPÉRIDINE À SUBSTITUTION 3 OU 4
  申请人：SK HOLDINGS CO LTD

  公开号：WO2009148291A2

  公开（公告）日：2009-12-10

  There are disclosed racemic or enantiomerically enriched 3- or 4-substituted piperidine compounds represented by the following structural formula (I) or any of their isomers, or pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions containing the subject compounds. The subject compounds are useful for the treatment of diseases of the central nervous system, particularly depression, anxiety and pain disorder.
• [EN] O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS<br/>[FR] INHIBITEURS D'O-GLYCOPROTÉINE-2-ACÉTAMIDO-2-DÉSOXY-3-D-GLYCOPYRANOSIDASE
  申请人：BIOGEN MA INC

  公开号：WO2019178191A1

  公开（公告）日：2019-09-19

  Described herein are compounds represented by formula (I") or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables Ar, Ra, Rb, m, n, Y1, Y2, R3 and R4 are defined herein.