Benzene, 1,1',1''-[[[(1S)-1-methyl-2-propynyl]oxy]methylidyne]tris- | 160309-10-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: Benzene, 1,1',1''-[[[(1S)-1-methyl-2-propynyl]oxy]methylidyne]tris-
• 英文别名: [[(2S)-but-3-yn-2-yl]oxy-diphenylmethyl]benzene
• CAS: 160309-10-4
• 化学式: C₂₃H₂₀O
• 分子量: 312.411
• InChiKey: HCNHSHVPQCUKEY-IBGZPJMESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Benzene, 1,1',1''-[[[(1S)-1-methyl-2-propynyl]oxy]methylidyne]tris- 、 alkaline earth salt of/the/ methylsulfuric acid 在 三丁基膦 作用下， 以 正庚烷 为溶剂， 反应 18.0h， 生成 (R)-4-Methoxy-6-methyl-6-phenyl-2-((S)-1-trityloxy-ethyl)-cyclohexa-2,4-dienone 、 (6S)-4-methoxy-6-methyl-6-phenyl-2-[(1S)-1-trityloxyethyl]cyclohexa-2,4-dien-1-one
  参考文献：
  名称：

  1,4-Asymmetric induction in the formation of cyclohexadienones by chirality transfer from a transiently installed chromium–stereospecific electrocyclic ring closure of a metal complexed vinyl ketene

  摘要：

  The cyclohexadienone annulation of a β,β-disubstituted vinyl chromium carbene complex and a chiral prop-2-ynylic ether results in high 1,4-asymmetric induction at the newly formed quaternary carbon; the stereochemical information from the prop-2-ynylic ether is initially transfered to the chromium coordination sphere and then to the quaternary carbon of the cyclohexa-2,4-dienone.

  DOI：

  10.1039/a604742d

文献信息

• 1,4-Asymmetric induction in the formation of cyclohexadienones by chirality transfer from a transiently installed chromium–stereospecific electrocyclic ring closure of a metal complexed vinyl ketene
  作者：Richard P. Hsung、John F. Quinn、Brian A. Weisenberg、William D. Wulff、Glenn P. A. Yap、Arnold L. Rheingold

  DOI：10.1039/a604742d

  日期：——

  The cyclohexadienone annulation of a β,β-disubstituted vinyl chromium carbene complex and a chiral prop-2-ynylic ether results in high 1,4-asymmetric induction at the newly formed quaternary carbon; the stereochemical information from the prop-2-ynylic ether is initially transfered to the chromium coordination sphere and then to the quaternary carbon of the cyclohexa-2,4-dienone.