1,4-Dimethyloctahydro-1H-cyclopenta[b]pyridine | 87401-54-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1,4-Dimethyloctahydro-1H-cyclopenta[b]pyridine
• 英文别名: 1,4-dimethyl-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyridine
• CAS: 87401-54-5
• 化学式: C₁₀H₁₉N
• 分子量: 153.26
• InChiKey: BEWXYPZHCLQGRZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF PROSTATE CANCER
  申请人：MOUNIR Zineb

  公开号：US20170283807A1

  公开（公告）日：2017-10-05

  The invention provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating subjects having TMPRSS2:ERG positive prostate cancer, which we show is amenable to therapeutic treatment with a PRMT5 inhibitor. Kits, methods of screening for candidate PRMT5 inhibitors, and associated methods of treatment are also provided.