2-(Methanesulfinyl)-2-methylbutane | 160390-12-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚砜
• 英文名称: 2-(Methanesulfinyl)-2-methylbutane
• 英文别名: 2-methyl-2-methylsulfinylbutane
• CAS: 160390-12-5
• 化学式: C₆H₁₄OS
• 分子量: 134.24
• InChiKey: IZPHZQITLDBZNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  36.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• TRANSDERMAL DRUG DELIVERY FORMULATION
  申请人：Nuvo Research Inc.

  公开号：EP1909772A1

  公开（公告）日：2008-04-16
• Transdermal Drug Delivery Formulation
  申请人：Singh Jagat

  公开号：US20080319092A1

  公开（公告）日：2008-12-25

  The present invention provides a transdermal formulation for the delivery of at least one active agent. The formulation includes (i) a first compound comprising an organic sulfoxide, and (ii) a second compound selected from the group consisting of a fatty acid ester, a fatty acid, an azone-related compound and mixtures thereof.
• TOPICAL NAIL FORMULATION
  申请人：Jagat Singh

  公开号：US20090215888A1

  公开（公告）日：2009-08-27

  The present invention relates to a topical nail formulation comprising at least one active agent (e.g., tolnaftate) and at least one nail penetration enhancer selected from the group consisting of a fatty acid, an azone derivative, and mixtures thereof. The invention also relates to the use of said topical nail formulation for the treatment of nail disorders such as onychomycosis. The invention further provides a method of enhancing the nail flux of an active agent by using a topical nail formulation containing the said penetration enhancer.
• [EN] TRANSDERMAL DRUG DELIVERY FORMULATION<br/>[FR] FORMULATION POUR L'ADMINISTRATION TRANSDERMIQUE DE MEDICAMENTS
  申请人：NUVO RES INC

  公开号：WO2007016766A1

  公开（公告）日：2007-02-15

  [EN] The present invention provides a transdermal formulation for the delivery of at least one active agent. The formulation includes (i) a first compound comprising an organic sulfoxide, and (ii) a second compound selected from the group consisting of a fatty acid ester, a fatty acid, an azone-related compound and mixtures thereof.
  [FR] La présente invention concerne une formulation transdermique pour l'administration d'un ou plusieurs agents actifs. La formulation comprend (i) un premier composé comprenant un sulfoxyde organique, et (ii) un second composé sélectionné parmi le groupe constitué par un ester d'acide gras, un acide gras, un composé lié à l'ozone et des mélanges de ces composés.
• [EN] TOPICAL NAIL FORMULATION<br/>[FR] FORMULATION TOPIQUE POUR LES ONGLES
  申请人：NUVO RES INC

  公开号：WO2007098591A2

  公开（公告）日：2007-09-07

  [EN] The present invention provides a topical nail formulation comprising at least one active agent and at least one penetration enhancer selected from the group consisting of a fatty acid, an azone-related compound and mixtures thereof.
  [FR] L'invention concerne une formulation topique pour les ongles qui comprend au moins un agent actif et au moins un agent augmentant la pénétration sélectionné dans le groupe comprenant un acide gras, un composé associé à l'azone et des mélanges de ceux-ci.