3-氮杂双环[3.2.0]庚-5-烯-2,7-二酮 | 226985-26-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吖庚因类
• 中文名称: 3-氮杂双环[3.2.0]庚-5-烯-2,7-二酮
• 英文名称: 3-azabicyclo<3.2.0>hept-5-en-2,7-dione
• 英文别名: 3-Azabicyclo[3.2.0]hept-5-ene-2,7-dione
• CAS: 226985-26-8
• 化学式: C₆H₅NO₂
• mdl: MFCD12923540
• 分子量: 123.111
• InChiKey: MOMYONAIHIHYCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  二氧化三碳 、 炔丙胺 在 amylenes 作用下， 以 氯仿 为溶剂， 以25%的产率得到3-氮杂双环[3.2.0]庚-5-烯-2,7-二酮
  参考文献：
  名称：

  One-step synthesis of new 3-oxa- or 3-azabicyclo[3.2.0]hept-5-en-2,7-dione and 5,9-dioxa- or 5,9-diazabicyclo[5.3.0]dec-1-en-3-methyliden-6,8-dione derivatives

  摘要：

  In this work we describe the synthesis of new compounds of a 3-oxa- or 3-azabicyclo[3.2.0]hept-5-en-2,7-dione (3a-d) and 5,9-dioxa- or 5,9-diazabicyclo[5.3.0]dec-1-en-3-methyliden-6,8-dione (4a-d) type with potential biological activity, obtained from the reaction of 2-propyn-1-ol or 2-propynylamine derivatives (1a-d) with carbon suboxide (2) in various molar ratios. (C) 1998 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0014-827x(98)00086-x

文献信息

• One-step synthesis of new 3-oxa- or 3-azabicyclo[3.2.0]hept-5-en-2,7-dione and 5,9-dioxa- or 5,9-diazabicyclo[5.3.0]dec-1-en-3-methyliden-6,8-dione derivatives
  作者：Leonardo Bonsignore、Giuseppe Loy、Daniela Secci、Mario Secci、Filippo Cottiglia

  DOI：10.1016/s0014-827x(98)00086-x

  日期：1998.11

  In this work we describe the synthesis of new compounds of a 3-oxa- or 3-azabicyclo[3.2.0]hept-5-en-2,7-dione (3a-d) and 5,9-dioxa- or 5,9-diazabicyclo[5.3.0]dec-1-en-3-methyliden-6,8-dione (4a-d) type with potential biological activity, obtained from the reaction of 2-propyn-1-ol or 2-propynylamine derivatives (1a-d) with carbon suboxide (2) in various molar ratios. (C) 1998 Elsevier Science S.A. All rights reserved.