| 82679-47-8

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• CAS: 82679-47-8
• 化学式: C₄H₈BrMgO*Cl*Mg
• 分子量: 236.074
• InChiKey: HLBWIHFBPMOYKV-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  2-(1-戊烯-3-基氧基)-1,3-苯并噻唑 、 在 copper(I) bromide 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 以90%的产率得到(E)-6-nonen-1-ol
  参考文献：
  名称：

  Selectivity in the allylic substitutions with organometallics through neighboring coordination. 2-(Allyloxy)benzothiazoles as SN2' electrophiles for regio- and stereoselective olefin syntheses

  摘要：

  DOI：

  10.1021/jo00144a016

文献信息

• Enantioselective synthesis of a C/D-ring synthon for the preparation of vitamin D3 metabolites
  作者：Susumi Hatakeyama、Hirotoshi Numata、Ken Osanai、Seiichi Takano

  DOI：10.1039/c39890001893

  日期：——

  The hydrindanol (2), a C/D-ring synthon of vitamin D3 metabolites, has been synthesized enantioselectively by the use of stereoselective epoxy alcohol-initiated polyalkene cyclisation as a key step.

  维生素D 3代谢产物的C / D环合成子羟醇（2）是通过立体选择性环氧醇引发的聚烯烃环化反应作为关键步骤而对映选择性合成的。
• Selectivity in allylic substitutions with organometallics through neighbouring coordination. Synthesis and reactions of copper(I) π-complexes with 2-allyloxybenzo-thiazoles
  作者：Vincenzo Calo、Luigi Lopez、Gianngelo Pesce

  DOI：10.1016/s0022-328x(00)81957-9

  日期：1982.5

  2-Allyloxybenzothiazoles react with CuBr to give stable CuI) π-complexes. These complexes undergo nucleophilic attack by organomagnesium compounds to give olefins with very high regio- and stereo-specificity.

  2- Allyloxybenzothiazoles与溴化亚铜反应，得到稳定的Cu我）π络合物。这些配合物受到有机镁化合物的亲核攻击，从而产生具有非常高的区域特异性和立体特异性的烯烃。
• A possible improvement for structure-based drug design illustrated by the discovery of a Tat HIV-1 inhibitor
  作者：Mickaël Montembault、Giang Vo-Thanh、Abdallah Deyine、Valérie Fargeas、Monique Villiéras、Ané Adjou、Didier Dubreuil、Didier Esquieu、Catherine Grégoire、Sandrine Opi、Jean-Marie Péloponèse、Grant Campbell、Jennifer Watkins、Jean de Mareuil、Anne-Marie Aubertin、Christian Bailly、Erwann Loret、Jacques Lebreton

  DOI：10.1016/j.bmcl.2003.12.095

  日期：2004.3

  The HIV-1 Tat protein is a promising target for AIDS therapy, due to its extra-cellular roles against the immune system. From the 2D-NMR structure of Tat, we have designed molecules, called TDS, able to bind to Tat and inhibit HIV-1 replication in vitro. This new family of antivirals is composed of a triphenylene aromatic ring substituted with at least one carbon chain bearing a succinimide group. These ligands are prepared from triphenylene or 2,6, 10-trimethylphenylene in 3-6 steps depending on the target molecule. (C) 2004 Elsevier Ltd. All rights reserved.
• Free Radical Approach to Directed Aldol-Type Reactions Promoted by Allylic O-Stannyl Ketyls
  作者：Eric J. Enholm、Yongping Xie、Khalil A. Abboud

  DOI：10.1021/jo00110a009

  日期：1995.3
• CALO, V.;LOPEZ, L.;PESCE, G.;CALIANNO, A., J. ORG. CHEM., 1982, 47, N 23, 4482-4485
  作者：CALO, V.、LOPEZ, L.、PESCE, G.、CALIANNO, A.

  DOI：——

  日期：——