Tert-butyl 9-amino-3-azabicyclo[3.3.1]nonane-3-carboxylate | 1198466-20-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: Tert-butyl 9-amino-3-azabicyclo[3.3.1]nonane-3-carboxylate
• CAS: 1198466-20-4
• 化学式: C₁₃H₂₄N₂O₂
• 分子量: 240.34
• InChiKey: QOQQKPHJTZRKSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  55.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] NOVEL PYRROLIDINYL AMIDE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE<br/>[FR] NOUVEAUX COMPOSÉS D'AMIDE PYRROLIDINYLE DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT D'UNE MALADIE AUTO-IMMUNE
  申请人：HOFFMANN LA ROCHE

  公开号：WO2020043271A1

  公开（公告）日：2020-03-05

  The present invention relates to compounds of formula (I) wherein R1, R2, R3 and R4 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

  本发明涉及公式（I）中R1、R2、R3和R4如本文所述的化合物及其药学上可接受的盐、对映体或非对映体，以及包括该化合物的组合物和使用该化合物的方法。
• NOVEL PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE
  申请人：F. Hoffmann-La Roche AG

  公开号：EP3847173A1

  公开（公告）日：2021-07-14
• NOVEL PYRROLIDINYL AMIDE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE
  申请人：F. Hoffmann-La Roche AG

  公开号：EP3844159A1

  公开（公告）日：2021-07-07
• PYRROLIDINYL AMIDE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE
  申请人：Hoffmann-La Roche Inc.

  公开号：US20210323977A1

  公开（公告）日：2021-10-21

  The present invention relates to compounds of formula (I) wherein R 1 , R 2 , R 3 and R 4 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
• PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE
  申请人：Hoffmann-La Roche Inc.

  公开号：US20210355122A1

  公开（公告）日：2021-11-18

  The present invention relates to compounds of formula (I), wherein R 1 , R 2 , R 3 and R 4 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.