2-Propylamino-4,6-diamino-s-triazin | 16274-79-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 2-Propylamino-4,6-diamino-s-triazin
• 英文别名: N-propyl-[1,3,5]triazine-2,4,6-triamine；2-N-propyl-1,3,5-triazine-2,4,6-triamine
• CAS: 16274-79-6
• 化学式: C₆H₁₂N₆
• 分子量: 168.201
• InChiKey: VTGYMXCBLHTEOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  103
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases
  申请人：Mannion James C.

  公开号：US20120295911A1

  公开（公告）日：2012-11-22

  The present invention includes compositions that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention.

  本发明包括用于治疗需要呼吸控制疾病或障碍的受体的组合物。本发明还包括一种治疗需要呼吸系统疾病或障碍的受体的方法，包括向受体施用本发明的药物制剂的治疗有效量。本发明还包括一种预防或稳定需要呼吸节律的受体的方法，包括向受体施用本发明的药物制剂的治疗有效量。
• Stabilizer composition
  申请人：Everlight USA, Inc.

  公开号：EP1439206A2

  公开（公告）日：2004-07-21

  A stabilizer composition which includes (a) a UV absorber of foramidine derivative, (b) a UV absorber of benzotriazole derivative, and (c) an antioxidant is disclosed. The stabilizer composition disclosed here are suitable for improving the stabilization of the organic polymers to against the degradation by light.

  本发明公开了一种稳定剂组合物，其中包括：(a) 福拉米丁衍生物紫外线吸收剂；(b) 苯并三唑衍生物紫外线吸收剂；(c) 抗氧化剂。这里公开的稳定剂组合物适用于提高有机聚合物的稳定性，防止光降解。
• Melamine-aldehyde-condensation product and method obtaining the same
  申请人：Borealis Agrolinz Melamine GmbH

  公开号：EP2743282A1

  公开（公告）日：2014-06-18

  The present invention relates to a melamine-aldehyde-condensation product obtainable by reacting at least one aldehyde, in particular formaldehyde, with a) Melamine, b) at least one melamine derivative of the general structure (I) and/or c) at least one melamine derivative of the general structure (II) wherein R1, R2, R3 and R4 mean independently from each other linear or branched C1-C20-alkyl, C5-C20-cyclo alkyl, C5-C20-aryl, C1-C20-alkylsubstituted C5-C20-aryl or cyclic amines, or wherein R1 and R2 or R3 and R4 form in each case together an alkyl ring, wherein in each case one or multiple carbon atoms can be substituted by one or multiple oxygen atoms, sulphur atoms and/or substituted nitrogen atoms and/or by one or multiple groups of the type -C(O)O-, -OC(O)-, -C(O)- and/or -OC(O)O-, and/or can be functionalized by one or multiple hydroxyl groups and/or mercapto groups; or an amide of a carboxylic acid or an imide of a cyclic dicarboxylic acid, and wherein R1, R2, R3 and R4 can be the same or different. The present invention relates also to a method for obtaining said melamine-aldehyde-condensation products and their use.

  本发明涉及一种三聚氰胺-醛缩合产物，可通过至少一种醛，特别是甲醛，与下列物质反应获得 a) 三聚氰胺 b) 至少一种一般结构为 (I) 的三聚氰胺衍生物 和/或 c) 一般结构 (II) 的至少一种三聚氰胺衍生物 其中 R1、R2、R3 和 R4 相互独立地表示直链或支链 C1-C20-烷基、C5-C20-环烷基、C5-C20-芳基、C1-C20-烷基取代的 C5-C20- 芳基或环胺，或其中 R1 和 R2 或 R3 和 R4 在每种情况下共同形成一个烷基环、在每种情况下，一个或多个碳原子可被一个或多个氧原子、硫原子和/或取代的氮原子和/或被一个或多个-C(O)O-、-OC(O)-、-C(O)-和/或-OC(O)O-类型的基团取代，和/或可被一个或多个羟基和/或巯基官能化；或羧酸的酰胺或环状二羧酸的酰亚胺，其中 R1、R2、R3 和 R4 可以相同或不同。本发明还涉及获得上述三聚氰胺-甲醛缩合产物的方法及其用途。
• Biguanide compositions and methods of treating metabolic disorders
  申请人：Elcelyx Therapeutics, Inc.

  公开号：US10028923B2

  公开（公告）日：2018-07-24

  Provided herein are methods for treating certain conditions, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administrating a composition comprising a biguanide or related heterocyclic compound, e.g., metformin. Also provided herein are biguanide or related heterocyclic compound compositions, and methods for the preparation thereof for use in the methods of the present invention. Also provided herein are compositions comprising metformin and salts thereof and methods of use.

  本文提供了通过施用包含双胍类或相关杂环化合物（如二甲双胍）的组合物来治疗某些疾病（包括糖尿病、肥胖症和其他代谢性疾病、失调或病症）的方法。本文还提供了双胍类或相关杂环化合物组合物及其用于本发明方法的制备方法。本文还提供了包含二甲双胍及其盐类的组合物和使用方法。
• High heat monomers and methods of use thereof
  申请人：SABIC GLOBAL TECHNOLOGIES B.V.

  公开号：US10435368B2

  公开（公告）日：2019-10-08

  High heat monomer compounds, methods for preparing compounds, and compositions derived from the compounds are provided. Also provided are materials and articles derived from the compounds.

  提供了高热单体化合物、制备化合物的方法以及由这些化合物衍生的组合物。此外，还提供了由这些化合物衍生的材料和物品。