1,4,4-Trimethyl-pyrazolin-2 | 45512-09-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑啉类
• 英文名称: 1,4,4-Trimethyl-pyrazolin-2
• 英文别名: 1,4,4-trimethyl-4,5-dihydro-1H-pyrazole；4-Trimethyl-az-pyrazoline；2,4,4-trimethyl-3H-pyrazole
• CAS: 45512-09-2
• 化学式: C₆H₁₂N₂
• 分子量: 112.175
• InChiKey: YDGDBQTTXLJDNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  15.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] PESTICIDAL HETEROCYCLIC COMPOUNDS<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES PESTICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2011051455A1

  公开（公告）日：2011-05-05

  The present invention relates to novel pesticidal azolidine derivatives as well as to oxazolidinone derivatives and their use as pesticides for combating animal parasites which occur in the agrochemical field and in the field of veterinary medicine, respectively. Formula (I) wherein X, m, R', Q, G, U, 1, A1 to A4 and R are as defined herein.

  本发明涉及新型杀虫杀虫剂氮杂环丙烷衍生物，以及噁唑烷酮衍生物及其作为农药用于对抗农业化学领域和兽医学领域中出现的动物寄生虫的用途。式（I）中X、m、R'、Q、G、U、1、A1至A4和R如本文所定义。
• SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUND, COMPOSITION CONTAINING THE SAME AND USE THEREOF
  申请人：Shenzhen TargetRx, Inc.

  公开号：US20220017539A1

  公开（公告）日：2022-01-20

  The present disclosure provides a substituted pyrazolo[1,5-a]pyridine compound, a composition including the same, and a use thereof. The substituted pyrazolo[1,5-a]pyridine compounds is a compound represented by formula (I) or the tautomers, stereoisomers, prodrugs, crystal forms, pharmaceutically acceptable salts, hydrates or solvates thereof. The compound of the present disclosure and composition thereof are useful for treating RET kinase-mediated diseases or conditions and have more excellent pharmacokinetic properties.

  本公开提供了一种取代的吡唑并[1,5-a]吡啶化合物，包括该化合物的组合物以及其用途。该取代的吡唑并[1,5-a]吡啶化合物是由式(I)表示的化合物或其互变异构体、立体异构体、前药、晶型、药学上可接受的盐、水合物或溶剂化合物。本公开的化合物及其组合物对于治疗RET激酶介导的疾病或症状非常有效，并具有更优异的药代动力学性能。
• Pesticidal Heterocyclic Compounds
  申请人：Murata Tetsuya

  公开号：US20110152332A1

  公开（公告）日：2011-06-23

  The present invention relates to novel pesticidal azolidine derivatives as well as to oxazolidinone derivatives and their use as pesticides for combating animal parasites which occur in the agrochemical field and in the field of veterinary medicine, respectively. wherein X, m, R′, Q, G, U, l, A 1 to A 4 and R are as defined herein.

  本发明涉及新型杀虫的氮杂环丙烷衍生物，以及噁唑烷衍生物，它们可以作为农药用于防治出现在农业化学领域和兽医学领域中的动物寄生虫。其中X，m，R'，Q，G，U，l，A1至A4和R的定义如本文所述。
• SYNTHESIS OF SUBSTITUTED PYRAZOLINE CARBOXAMIDINE DERIVATIVES
  申请人：van Loevezijn Arnold

  公开号：US20130060041A1

  公开（公告）日：2013-03-07

  This invention relates to organic chemistry, in particular to processes for the preparation of pyrazoline carboxamidine derivatives of formula (I), known as potent 5-HT6 antagonists. The invention also relates to novel intermediates of these compounds. wherein the symbols have the meanings given in the description.

  本发明涉及有机化学，特别是关于制备式(I)的吡唑啉羧酰胺衍生物的过程，这些衍生物被称为有效的5-HT6受体拮抗剂。本发明还涉及这些化合物的新型中间体。其中符号的含义如描述所示。
• PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF
  申请人：Qingdao KingAgroot Chemical Compound Co., Ltd.

  公开号：EP3747870A1

  公开（公告）日：2020-12-09

  The invention belongs to the technical field of agricultural chemicals, and in particular relates to a pyridazinol compound represented by the Formula I, a derivative, preparation method, herbicidal composition and use thereof. The compound, derivative and herbicidal composition thereof have very high herbicidal activity and selectivity, and are safe for crops,

  本发明属于农药技术领域，尤其涉及一种由式 I 表示的哒嗪类化合物、其衍生物、制备方法、除草组合物及其用途。本发明的化合物、衍生物和除草组合物具有极高的除草活性和选择性，对作物安全、