3-Piperidinecarboxylic acid, 1-(2-((2,3-dichloro-4-((1R,2R)-2-(((3-(2-oxo-1-pyrrolidinyl)propyl)amino)carbonyl)cyclopropyl)phenyl)thio)phenyl)-, rel- | 350592-74-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 3-Piperidinecarboxylic acid, 1-(2-((2,3-dichloro-4-((1R,2R)-2-(((3-(2-oxo-1-pyrrolidinyl)propyl)amino)carbonyl)cyclopropyl)phenyl)thio)phenyl)-, rel-
• 英文别名: 1-[2-[2,3-dichloro-4-[(1R,2R)-2-[3-(2-oxopyrrolidin-1-yl)propylcarbamoyl]cyclopropyl]phenyl]sulfanylphenyl]piperidine-3-carboxylic acid
• CAS: 350592-74-4
• 化学式: C₂₉H₃₃Cl₂N₃O₄S
• 分子量: 590.6
• InChiKey: CYHYOQQJILLXPV-QYAPWVIVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  39
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  115
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Combination for the treatment of airway disorders
  申请人：Hanauer Guido

  公开号：US20050165041A1

  公开（公告）日：2005-07-28

  The invention relates to the combination of proton pump inhibitors and airway therapeutics for the treatment of airway disorders.

  本发明涉及质子泵抑制剂和气道治疗剂的组合，用于治疗气道疾病。
• NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS
  申请人：ALTANA Pharma AG

  公开号：EP1506016A2

  公开（公告）日：2005-02-16
• Novel combination for the treatment of airway disorders
  申请人：Hanauer Guido

  公开号：US20050222193A1

  公开（公告）日：2005-10-06

  The invention relates to the combination of reversible proton pump inhibitors and airway therapeutics for the treatment of airway disorders.
• [EN] NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS<br/>[FR] NOUVELLE COMBINAISON DESTINEE AU TRAITEMENT DES TROUBLES DES VOIES AERIENNES
  申请人：ALTANA PHARMA AG

  公开号：WO2003094967A2

  公开（公告）日：2003-11-20

  The invention relates to the combination of reversible proton pump inhibitors and airway therapeutics for the treatment of airway disorders.
• [EN] THE USE OF (S) - PANTOPRAZOLE MAGNESIUM FOR THE TREATMENT OF AIRWAY DISORDERS<br/>[FR] UTILISATION DE (S)-PANTOPRAZOLE MAGNESIUM POUR LE TRAITEMENT DE TROUBLES DES VOIES RESPIRATOIRES
  申请人：ALTANA PHARMA AG

  公开号：WO2005074932A1

  公开（公告）日：2005-08-18

  The invention relates to the use of (S)-pantoprazole magnesium and its hydrates in the treatment of airway disorders and to the combination of (S)-pantoprazole magnesium and its hydrates and airway therapeutics for the treatment of airway disorders.