(E)-N-(2-oxo-1-phenylpiperidin-3-yl)-2-phenylethene-sulfonamide | 1259536-35-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: (E)-N-(2-oxo-1-phenylpiperidin-3-yl)-2-phenylethene-sulfonamide
• 英文别名: (E)-N-(2-oxo-1-phenylpiperidin-3-yl)-2-phenylethenesulfonamide
• CAS: 1259536-35-0
• 化学式: C₁₉H₂₀N₂O₃S
• 分子量: 356.445
• InChiKey: GPFLFHYXPCLLBL-FYWRMAATSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  74.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY
  申请人：CASTELLS BOLIART Josep

  公开号：US20120142930A1

  公开（公告）日：2012-06-07

  Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides useful for being biologically and pharmacologically screened, and to contribute to the exploration and identification of new lead molecules that are capable of modulating the functional activity of a biological target.

  小说化合物不断被寻求用于治疗和预防疾病和紊乱。该发明涉及对N-(2-氧代-1-苯基哌啶-3-基)磺酰胺的生物和药理筛选，以及对探索和识别能够调节生物靶标功能活性的新领先分子的贡献。
• LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR DRUG DISCOVERY
  申请人：CASTELLS BOLIART JOSEP

  公开号：US20120129888A1

  公开（公告）日：2012-05-24

  Novel compounds are continually sought after to treat and prevent disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides useful for contributing to the search and identification of new lead compounds which can modulate the functional activity of a biological target.

  小说化合物不断被寻求以治疗和预防疾病。该发明涉及对N-(2-氧代-1-苯基哌啶-3-基)磺酰胺的使用，有助于寻找和识别可以调节生物靶点功能活性的新领先化合物。
• LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY
  申请人：CASTELLS BOLIART JOSEP

  公开号：US20120122708A1

  公开（公告）日：2012-05-17

  New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides which can be biologically and pharmacologically traced, in order to be used in the search for, and identification of, new lead compounds that can modulate the functional activity of a biological target.

  不断寻找治疗和预防疾病的新化合物。该发明涉及N-(2-氧代-1-苯基哌啶-3-基)磺酰胺，可以在生物和药理学上追踪，以用于寻找和识别可以调节生物靶点的功能活性的新领先化合物。
• N-(1-PHENYL-2-OXO-3-PIPERIDYL SULPHONAMIDE LIBRARIES FOR DRUG DISCOVERY
  申请人：Institut Univ. de Ciència i Tecnologia, S.A.

  公开号：EP2447251A1

  公开（公告）日：2012-05-02

  Novel compounds are continually sought after to treat and prevent disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides useful for contributing to the search and identification of new lead compounds which can modulate the functional activity of a biological target.

  人们一直在寻找新的化合物来治疗和预防疾病。本发明涉及 N-(2-氧代-1-苯基哌啶-3-基)磺酰胺，有助于寻找和鉴定可调节生物靶标功能活性的新先导化合物。
• N-(1-PHENYL-2-OXO-3-PIPERIDYL)SULPHONAMIDE LIBRARIES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY
  申请人：Institut Univ. de Ciència i Tecnologia, S.A.

  公开号：EP2450349A1

  公开（公告）日：2012-05-09

  New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides which can be biologically and pharmacologically traced, in order to be used in the search for, and identification of, new lead compounds that can modulate the functional activity of a biological target.

  人们一直在寻找新的化合物来治疗和预防疾病。本发明涉及 N-(2-氧代-1-苯基哌啶-3-基)磺酰胺，可对其进行生物学和药理学追踪，以用于寻找和鉴定可调节生物靶标功能活性的新先导化合物。