2,3-Dimethylpiperidine hydrochloride | 1087730-30-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2,3-Dimethylpiperidine hydrochloride
• 英文别名: 2,3-dimethylpiperidine;hydrochloride
• CAS: 1087730-30-0
• 化学式: C7H16ClN
• mdl: MFCD19160661
• 分子量: 149.66
• InChiKey: UECZGGHXYWFHDD-UHFFFAOYSA-N

物化性质

• 熔点：
  246-247 °C

计算性质

• 辛醇/水分配系数(LogP)：
  1.44
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• 3-SUBSTITUTED PIPERIDINE COMPOUNDS FOR CBL-B INHIBITION, AND USE OF A CBL-B INHIBITOR IN COMBINATION WITH A CANCER VACCINE AND/OR ONCOLYTIC VIRUS
  申请人：Nurix Therapeutics, Inc.

  公开号：EP3953346A1

  公开（公告）日：2022-02-16
• [EN] HAFNIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION<br/>[FR] PRÉCURSEURS CONTENANT DU HAFNIUM POUR UN DÉPÔT EN PHASE VAPEUR
  申请人：AIR LIQUIDE

  公开号：WO2013177284A1

  公开（公告）日：2013-11-28

  Disclosed are hafnium-containing precursors and methods of synthesizing the same. The precursors may be used to deposit hafnium oxide, hafnium silicon oxide and hafnium-metal oxide containing layers using vapor deposition methods such as chemical vapor deposition or atomic layer deposition.
• [EN] TITANIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION<br/>[FR] PRÉCURSEURS CONTENANT DU TITANE POUR UN DÉPÔT EN PHASE VAPEUR
  申请人：AIR LIQUIDE

  公开号：WO2013177292A1

  公开（公告）日：2013-11-28

  Disclosed are titanium-containing precursors and methods of synthesizing the same. The precursors may be used to deposit titanium oxide, titanium silicon oxide and titanium-metal oxide containing layers using vapor deposition methods such as chemical vapor deposition or atomic layer deposition.
• [EN] ZIRCONIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION<br/>[FR] PRÉCURSEURS CONTENANT DU ZIRCONIUM POUR LE DÉPÔT EN PHASE VAPEUR
  申请人：AIR LIQUIDE

  公开号：WO2013177269A2

  公开（公告）日：2013-11-28

  Disclosed are zirconium-containing precursors and methods of synthesizing the same. The precursors may be used to deposit zirconium oxide, zirconium silicon oxide and zirconium-metal oxide containing layers using vapor deposition methods such as chemical vapor deposition or atomic layer deposition.
• [EN] 3-SUBSTITUTED PIPERIDINE COMPOUNDS FOR CBL-B INHIBITION, AND USE OF A CBL-B INHIBITOR IN COMBINATION WITH A CANCER VACCINE AND/OR ONCOLYTIC VIRUS<br/>[FR] COMPOSÉS DE PIPÉRIDINE SUBSTITUÉS EN POSITION 3 POUR L'INHIBITION DE CBL-B, ET UTILISATION D'UN INHIBITEUR DE CBL-B EN COMBINAISON AVEC UN VACCIN CONTRE LE CANCER ET/OU UN VIRUS ONCOLYTIQUE
  申请人：NURIX THERAPEUTICS INC

  公开号：WO2020210508A1

  公开（公告）日：2020-10-15

  Compounds, compositions, and methods for use in inhibiting the E3 enzyme Cbl-b in the ubiquitin proteasome pathway are disclosed. The compounds, compositions, and methods can be used to modulate the immune system, to treat diseases amenable to immune system modulation, and for treatment of cells in vivo, in vitro, or ex vivo. Also disclosed are pharmaceutical compositions comprising a Cbl-b inhibitor and a cancer vaccine, as well as methods for treating cancer using a Cbl-b inhibitor and a cancer vaccine; and pharmaceutical compositions comprising a Cbl-b inhibitor and an oncolytic virus, as well as methods for treating cancer using a Cbl-b inhibitor and an oncolytic virus.