钙荧光探针Fluo-8,AM | 1345980-40-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 中文名称: 钙荧光探针Fluo-8,AM
• 英文名称: Fluo-8 AM
• 英文别名: acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-4-[3-(acetyloxymethoxy)-6-oxoxanthen-9-yl]-2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]phenoxy]ethoxy]anilino]acetate
• CAS: 1345980-40-6
• 化学式: C₅₀H₅₀N₂O₂₃
• 分子量: 1046.9
• InChiKey: BKYHTWFRZPRHNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  75
• 可旋转键数：
  36
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  297
• 氢给体数：
  0
• 氢受体数：
  25

文献信息

• PROCESSES FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS
  申请人：Enzo Life Sciences, Inc.

  公开号：EP2975405A1

  公开（公告）日：2016-01-20

  This invention relates to multi-drug resistance (MDR) in cells, and the use of certain xanthene compounds for determining drug resistance in cells and the effect of test compounds on cell membrane transport by the membrane transporters MDR1, MRP and BCRP. Processes and kits for making these determinations and measuring these effects are described and provided.

  本发明涉及细胞的多重耐药性（MDR），以及使用某些呫吨化合物测定细胞的耐药性和测试化合物对膜转运体 MDR1、MRP 和 BCRP 的细胞膜转运的影响。本文描述并提供了进行这些测定和测量这些影响的工艺和试剂盒。
• Processes and kits for determining multi-drug resistance of cells
  申请人：Lebedeva Irina

  公开号：US20110269168A1

  公开（公告）日：2011-11-03

  This invention relates to multi-drug resistance (MDR) in cells, and the use of certain xanthene compounds for determining drug resistance in cells and the effect of test compounds on cell membrane transport by the membrane transporters MDR1, MRP and BCRP. Processes and kits for making these determinations and measuring these effects are described and provided.
• FLUORESCENT ION INDICATORS AND THEIR APPLICATIONS
  申请人：AAT Bioquest, Inc.

  公开号：US20140080170A1

  公开（公告）日：2014-03-20

  Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations.
• US8445271B2
  申请人：——

  公开号：US8445271B2

  公开（公告）日：2013-05-21
• US8779165B2
  申请人：——

  公开号：US8779165B2

  公开（公告）日：2014-07-15