1-(2-Hydroxyethylsulfonyl)pentan-3-one | 1122004-58-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: 1-(2-Hydroxyethylsulfonyl)pentan-3-one
• CAS: 1122004-58-3
• 化学式: C₇H₁₄O₄S
• 分子量: 194.252
• InChiKey: FLJYHFAGOGDKBH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  79.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• SULFUR-CONTAINING COMPOUND, METHOD OF PREPARATION AND PHARMACEUTICAL USES THEREOF
  申请人：Sheu Jyh-Horng

  公开号：US20090062285A1

  公开（公告）日：2009-03-05

  The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2. This invention also describes a series of chemical analogues of the said sulfur-containing compound and the preparation of these compounds.

  该发明涉及一种含硫化合物及其制备方法。该发明还涉及利用该含硫化合物抑制诱导型一氧化氮合酶和/或环氧合酶-2以及治疗与诱导型一氧化氮合酶和/或环氧合酶-2相关的疾病。该发明还描述了该含硫化合物的一系列化学类似物及这些化合物的制备方法。
• Sulfur-containing compound, method of preparation and pharmaceutical uses thereof
  申请人：National Sun Yat-Sen University

  公开号：EP2030968B1

  公开（公告）日：2017-02-22
• PHARMACEUTICAL USES OF SULFUR-CONTAINING COMPOUND
  申请人：NATIONAL SUN YAT-SEN UNIVERSITY

  公开号：US20160009642A1

  公开（公告）日：2016-01-14

  The invention relates to uses of the sulfur-containing compound in inhibiting activities of a factor related to cancer metastasis and/or growth. Preferably, the invention relates to uses of the sulfur-containing compound in inhibiting lung cancer metastasis and/or growth.
• US8399661B2
  申请人：——

  公开号：US8399661B2

  公开（公告）日：2013-03-19
• US8722745B2
  申请人：——

  公开号：US8722745B2

  公开（公告）日：2014-05-13