Einecs 299-284-9 | 75656-48-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并噻唑类
• 英文名称: Einecs 299-284-9
• 英文别名: 6-phenyl-3,5,6,7-tetrahydro-2H-imidazo[2,1-b][1,3]thiazole-1,4,7-triium;phosphate
• CAS: 75656-48-3
• 化学式: C11H15N2O4PS
• 分子量: 302.29
• InChiKey: QEMMFDPTLWDHKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.32
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  145
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• PHARMACEUTICAL COMBINATIONS, PHARMACEUTICAL COMPOSITIONS, MEDICAMENT AND METHOD FOR THE TREATMENT OF ANIMALS
  申请人：Ouro Fino Participações E Empreendimentos S/A.

  公开号：EP2497467A1

  公开（公告）日：2012-09-12

  This invention relates to antihelminthic pharmaceutical combinations comprising iodinated aromatic compounds, such as disophenol or nitroxynil, with other pharmaceutical active ingredients targeting the treatment of animals. More specifically, this invention concerns pharmaceutical compositions comprising disophenol or nitroxynil with at least one other pharmaceutical antihelminthic active ingredient, selected from among benzimidazoles, thiabendazole, levamisole or tetramisole salts, avermectins or milbemycins and, even more preferably, levamisole salts selected from between levamisole chloride or phosphate. This invention also relates to medications and a method for treating animals comprising such antihelminthic medications.

  本发明涉及由碘化芳香族化合物，如二苯酚或硝基苯腈，与其他药物活性成分组成的抗蠕虫药物组合物，用于治疗动物。更具体地说，本发明涉及的药物组合物由二苯酚或硝磺嘧啶与至少一种其他药物抗蠕虫活性成分组成，这些活性成分选自苯并咪唑类、噻苯达唑、左旋咪唑或四咪唑盐、阿维菌素或米贝菌素，更优选的是选自氯化左旋咪唑或磷酸左旋咪唑的左旋咪唑盐。 本发明还涉及治疗动物的药物和方法，其中包括此类抗蠕虫药物。