Einecs 233-284-1 | 10103-48-7

• 物质功能分类: 无机化工 - 无机盐 - 磷化物、金属的磷酸、偏磷酸、次磷酸和焦磷酸盐
• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 过渡金属氧阴离子化合物
• 英文名称: Einecs 233-284-1
• 英文别名: copper;copper(1+);phosphate
• CAS: 10103-48-7
• 化学式: Cu*Cu*O₄P
• 分子量: 222.063
• InChiKey: JHXHVSZOEWSIIH-UHFFFAOYSA-K

物化性质

• 颜色/状态：
  Light-blue powder
• 溶解度：
  Soluble in acids, ammonium hydroxide; insoluble in water
• 分解：
  DANGEROUS. WHEN HEATED TO DECOMPOSITION, CAN EMIT HIGHLY TOXIC FUMES OF/PHOSPHORUS OXIDES/. /PHOSPHATES/

计算性质

• 辛醇/水分配系数(LogP)：
  -2.83
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  86.2
• 氢给体数：
  0
• 氢受体数：
  4

ADMET

毒理性

• 解毒与急救

基本治疗：建立专利气道。如有必要，进行吸痰。观察呼吸不足的迹象，如有必要，协助通气。通过非循环呼吸面罩以10至15升/分钟的速度给予氧气。监测休克并视需要进行治疗……。对于眼睛污染，立即用水冲洗眼睛。在运输过程中，用生理盐水连续冲洗每只眼睛……。不要使用催吐剂。对于误食，如果患者能够吞咽，有强烈的干呕反射且不流口水，则用水冲洗口腔，并给予5毫升/千克，最多200毫升的水进行稀释。给予活性炭……。/铜及其相关化合物/

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Copper and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

高级治疗：对于失去意识的患者，考虑进行口咽或鼻咽气管插管以控制气道。开始静脉输液，使用乳酸钠林格氏液/血浆替代液（SRP）："保持开放"，最低流速。观察液体过载的迹象。对于伴有低血容量迹象的低血压，谨慎给予液体。如果血容量正常但血压低，考虑使用血管加压药。注意液体过载的迹象...使用丙美卡因盐酸盐协助眼部冲洗...铜及其相关化合物/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Start an IV with lactated Ringer's /SRP: "To keep open", minimal flow rate/. Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine, hydrochloride to assist eye irrigation ... . /Copper and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 生态毒性值

EC50 Selenastrum capricornatum (green alga) 85 μg/l/14天/细胞体积生物测试/

EC50 Selenastrum capricornatum (green alga) 85 ug/l/14 days /Cell volume bioassay/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 生态毒性值

EC50 假微型海链藻（海藻，盐水）5 微克/升/72小时/生长速率生物测试/

EC50 Thalassiosira pseudonana (alga, saltwater) 5 ug/l/72 hr /Growth rate bioassay/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 生态毒性值

EC50 裸藻属（海水藻类）33微克/升/96小时/生长速率生物测试法/

EC50 Nitschia closterium (alga, saltwater) 33 ug/l/96 hr /Growth rate bioassay/

来源:Hazardous Substances Data Bank (HSDB)

反应信息

• 作为产物：
  描述：

  copper(II) orthophosphate 以 melt 为溶剂， 生成 copper(II) pyrophosphate 、 Einecs 233-284-1
  参考文献：
  名称：

  Crystalline Copper Phosphates: Synthesis and Thermal Stability

  摘要：

  The syntheses of Cu(PO3)2, Cu2P2O7, Cu4P2O9, Cu5P2O10, Cu3(PO4)2, and Cu2PO4 were accomplished by several new solid‐state routes. Attempts to synthesize CuPO3 were unsuccessful, and it is suspected that this compound, which is reported in the literature, may not exist. The thermal stabilities of Cu(PO3)2, Cu2P2O7 and Cu3(PO4)2 were examined, and their decomposition was concluded to be strongly dependent on slow kinetics.

  DOI：

  10.1111/j.1151-2916.1997.tb03241.x

文献信息

• Crystalline Copper Phosphates: Synthesis and Thermal Stability
  作者：Carlos E. Bamberger、E. D. Specht、Lawrence M. Anovitz

  DOI：10.1111/j.1151-2916.1997.tb03241.x

  日期：——

  The syntheses of Cu(PO3)2, Cu2P2O7, Cu4P2O9, Cu5P2O10, Cu3(PO4)2, and Cu2PO4 were accomplished by several new solid‐state routes. Attempts to synthesize CuPO3 were unsuccessful, and it is suspected that this compound, which is reported in the literature, may not exist. The thermal stabilities of Cu(PO3)2, Cu2P2O7 and Cu3(PO4)2 were examined, and their decomposition was concluded to be strongly dependent on slow kinetics.
• Synthesis, Structure, and Magnetic Properties of a Novel Mixed-Valence Copper(I/II) Phosphate, Cu2PO4
  作者：Kristen M. S. Etheredge、Shiou-Jyh Hwu

  DOI：10.1021/ic00124a016

  日期：1995.9

  Via phase compatibility studies, a novel mixed-valence copper(I/II) phosphate, Cu2PO4, has been isolated from a direct reaction of (Cu2O)-O-I, (CuO)-O-II, and P2O5 in fused silica. The single-crystal X-ray diffraction shows that the title compound crystallizes in a triclinic (P (1) over bar) unit cell, with lattice dimensions a = 6.145(2) Angstrom, b = 9.348(2) Angstrom, c = 6.009(1) Angstrom, alpha = 96.46(2)degrees, beta = 100.16(2)degrees, gamma = 73.97(2)degrees, V = 325.8(1) Angstrom(3): Z = 4. The structure has been refined by the least-squares method to R = 0.019, R(w) = 0.030, and GOF = 1.43 for 128 variables. The four copper atoms in each asymmetric unit adopt three distorted coordination geometries that are consistent with the corresponding electronic states, e.g., square pyramidal Cu(1)O-II(5), octahedral Cu(2)O-II(6), and linear Cu(3,4)O-I(2). A low-dimensional framework exists consisting of arrays of nearly parallel CuO2 units which are separated by the nonmagnetic, closed-shell P5+ cation in PO4 tetrahedra. Closely spaced CuO2 chains and a relatively short Cu-I-Cu-I distance, e.g., 2.737 Angstrom for Cu(3)-Cu(3), are attributed to the bond strength of the cross-linked PO4 tetrahedra. In the extended Cu(I/II)-O framework, short linkages of Cu-I-O-Cu-II-O-Cu-I and Cu-II-O-Cu-II, composed of regular Cu-O bonds (1.86-1.99 Angstrom), are interconnected through long Cu-II-O bonds (2.36-2.74 Angstrom). The magnetic measurements indicate that the Cu-O framework exhibits a spin 1/2 ground state and an antiferromagnetic ordering with a broad susceptibility maximum between 95 and 105 K. The results of stoichiometric synthesis, thermal analysis, and bond valence sum calculations of the title compound are also discussed.