3-{5-(3-ethoxycarbonyl-4-oxopiperidinyl)pentyl}-6-(3-ethyl-4-methylanilino)uracil | 496943-22-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 3-{5-(3-ethoxycarbonyl-4-oxopiperidinyl)pentyl}-6-(3-ethyl-4-methylanilino)uracil
• 英文别名: ethyl 1-[5-[6-(3-ethyl-4-methylanilino)-2,4-dioxo-1H-pyrimidin-3-yl]pentyl]-4-oxopiperidine-3-carboxylate
• CAS: 496943-22-7
• 化学式: C₂₆H₃₆N₄O₅
• 分子量: 484.596
• InChiKey: MPWHSCJOYZAQGC-UHFFFAOYSA-N

物化性质

• 密度：
  1.202±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  35
• 可旋转键数：
  12
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  108
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• N3-substituted 6-anilinopyrimidines and methods to treat-Gram-positive bacterial and mycoplasmal infections
  申请人：——

  公开号：US20030114445A1

  公开（公告）日：2003-06-19

  Compounds useful for treating Gram-positive bacterial and mycoplasmal infections are disclosed. The compounds have the general formulae shown below. 1

  本发明揭示了用于治疗革兰氏阳性细菌和支原体感染的化合物。该化合物具有下面所示的一般式。1
• [EN] N3-SUBSTITUTED 6-ANILINOPYRIMIDINES AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS<br/>[FR] 6-ANILINOPYRIMIDINES N3-SUBSTITUEES ET METHODES DE TRAITEMENT D'INFECTIONS GRAM-POSITIF BACTERIENNES ET MYCOPLASMIQUES
  申请人：UNIV MASSACHUSETTS

  公开号：WO2003011297A1

  公开（公告）日：2003-02-13

  Compounds useful for treating Gram-positive bacterial and mycoplasmal infections are disclosed. The compounds have the general formulae (I) and (II).
• [EN] MAMMALIAN GENES INVOLVED IN INFECTION<br/>[FR] GÈNES DE MAMMIFÈRE IMPLIQUÉS DANS L'INFECTION
  申请人：ZIRUS INC

  公开号：WO2010134939A2

  公开（公告）日：2010-11-25

  The present invention relates to nucleic acid sequences and cellular proteins encoded by these sequences that are involved in infection or are otherwise associated with the life cycle of one or more pathogens.