1-(1,1,2,2,3,3,3-Heptadeuteriopropyl)-4-(3-methylsulfonylphenyl)piperidine;hydrochloride | 1361311-55-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-(1,1,2,2,3,3,3-Heptadeuteriopropyl)-4-(3-methylsulfonylphenyl)piperidine;hydrochloride
• CAS: 1361311-55-8
• 化学式: C15H24ClNO2S
• 分子量: 324.9
• InChiKey: YGRHOYQMBLLGEV-DWPKPNNESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  45.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• DEUTERATED ANALOGS OF PRIDOPIDINE USEFUL AS DOPAMINERGIC STABILIZERS
  申请人：SONESSON Clas

  公开号：US20160095847A1

  公开（公告）日：2016-04-07

  The present invention provides novel deuterated analogs of Pridopidine, i.e. 4-(3-methanesulfonyl-phenyl)-1-propyl-piperidine. Pridopidine is a drug substance currently in clinical development for the treatment of Huntington's disease. In other aspects the invention relates to pharmaceutical compositions comprising a deuterated analog of Pridopidine of the invention, and to therapeutic applications of these analogs.