Acetic acid (2S,4aS,5S)-5-(tert-butyl-dimethyl-silanyloxy)-1,1,4a-trimethyl-7-oxo-1,2,3,4,4a,5,6,7-octahydro-naphthalen-2-yl ester | 160144-60-5

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: Acetic acid (2S,4aS,5S)-5-(tert-butyl-dimethyl-silanyloxy)-1,1,4a-trimethyl-7-oxo-1,2,3,4,4a,5,6,7-octahydro-naphthalen-2-yl ester
• CAS: 160144-60-5
• 化学式: C₂₁H₃₆O₄Si
• 分子量: 380.6
• InChiKey: XHFNDCHCPGBYTF-WFXMLNOXSA-N

反应信息

• 作为反应物：
  描述：

  Acetic acid (2S,4aS,5S)-5-(tert-butyl-dimethyl-silanyloxy)-1,1,4a-trimethyl-7-oxo-1,2,3,4,4a,5,6,7-octahydro-naphthalen-2-yl ester 在 sodium tetrahydroborate 、 ceric chloride heptahydrate 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 生成 Acetic acid (2S,4aS,5S,7R)-5-(tert-butyl-dimethyl-silanyloxy)-7-hydroxy-1,1,4a-trimethyl-1,2,3,4,4a,5,6,7-octahydro-naphthalen-2-yl ester
  参考文献：
  名称：

  Chemobiological transformations of octalone and hydrindenone derivatives

  摘要：

  Examples are given for allylic hydroxylations with Rhizopus arrhizus ATCC 11145. Chemical allylic hydroxylations are compared with microbiological ones. Stereoselective lipase-catalyzed hydrolyses are used efficiently.

  DOI：

  10.1016/s0040-4020(01)85563-0
• 作为产物：
  描述：

  Acetic acid (2S,4aS,5S)-5-(tert-butyl-dimethyl-silanyloxy)-1,1,4a-trimethyl-1,2,3,4,4a,5,6,7-octahydro-naphthalen-2-yl ester 在 chromium(VI) oxide 、 叔丁基过氧化氢 作用下， 以 二氯甲烷 为溶剂， 反应 6.0h， 以64%的产率得到Acetic acid (2S,4aS,5S)-5-(tert-butyl-dimethyl-silanyloxy)-1,1,4a-trimethyl-7-oxo-1,2,3,4,4a,5,6,7-octahydro-naphthalen-2-yl ester
  参考文献：
  名称：

  Chemobiological transformations of octalone and hydrindenone derivatives

  摘要：

  Examples are given for allylic hydroxylations with Rhizopus arrhizus ATCC 11145. Chemical allylic hydroxylations are compared with microbiological ones. Stereoselective lipase-catalyzed hydrolyses are used efficiently.

  DOI：

  10.1016/s0040-4020(01)85563-0