[3-(difluoromethyl)-5-fluoro-1-methaneyl-1H-pyrazol-4-yl][2-(1-phenylpropyl)piperidin-1-yl]methanone | 1373315-41-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: [3-(difluoromethyl)-5-fluoro-1-methaneyl-1H-pyrazol-4-yl][2-(1-phenylpropyl)piperidin-1-yl]methanone
• 英文别名: [3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazol-4-yl][2-(1-phenylpropyl)piperidin-1-yl]methanone；[3-(Difluoromethyl)-5-fluoro-1-methylpyrazol-4-yl]-[2-(1-phenylpropyl)piperidin-1-yl]methanone
• CAS: 1373315-41-3
• 化学式: C₂₀H₂₄F₃N₃O
• 分子量: 379.425
• InChiKey: XZGDGXPPLCQBFN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  38.1
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• N-HETARYL(THIO)CARBONYL-2-(BENZOCYCLOALKEN-1-YL)CYCLAMINES AND THEIR USE AS FUNGICIDES
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US20160244433A1

  公开（公告）日：2016-08-25

  The present invention relates to fungicidal N-hetarylcarbonyl-2-(benzocycloalken-1-yl)piperidines or pyrrolidines of formula (I), and their thiocarbonyl derivatives, wherein A represents a carbo-linked, unsaturated or partially saturated, 5-membered heterocyclyl group that can be substituted by up to four groups R that can be the same or different; T represents 0 or S; n represents 1 or 2; m represents 1, 2 or 3; p represents 1, 2, 3 or 4, L 1 and L 2 independently represent CZ 4 Z 5 , NZ 6 , 0, S, S(O) or S(0) 2 ; and R and Z 1 -Z 6 are as defined in the claims; their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.

  本发明涉及式（I）的杀菌N-杂环酰基-2-(苯并环烷-1-基)哌啶或吡咯烷，以及它们的硫代酰基衍生物，其中A代表一个碳链连接的不饱和或部分饱和的5元杂环基团，该基团可以被多达四个可以相同或不同的R基团取代；T代表0或S；n代表1或2；m代表1、2或3；p代表1、2、3或4；L1和L2分别独立地表示CZ4Z5、NZ6、0、S、S(O)或S(0)2；R和Z1-Z6如权利要求中所定义；本发明还涉及制备这些化合物的方法和中间体化合物，以及它们作为杀菌剂的用途，特别是以杀菌剂组合物的形式和使用这些化合物或它们的组合物控制植物的植物病原真菌的方法。
• N-hetaryl(thio)carbonyl-2-(benzocycloalken-1-yl)cyclamines and their use as fungicides
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US10626109B2

  公开（公告）日：2020-04-21

  The present invention relates to fungicidal N-hetarylcarbonyl-2-(benzocycloalken-1-yl)piperidines or pyrrolidines of formula (I), and their thiocarbonyl derivatives, wherein A represents a carbo-linked, unsaturated or partially saturated, 5-membered heterocyclyl group that can be substituted by up to four groups R that can be the same or different; T represents 0 or S; n represents 1 or 2; m represents 1, 2 or 3; p represents 1, 2, 3 or 4, L1 and L2 independently represent CZ4Z5, NZ6, 0, S, S(O) or S(0)2; and R and Z1-Z6 are as defined in the claims; their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.

  本发明涉及式(I)的杀真菌 N-芳羰基-2-(苯并环烯-1-基)哌啶或吡咯烷及其硫代羰基衍生物，其中 A 代表与碳水化合物连接的、不饱和或部分饱和的 5 元杂环基团，该杂环基团最多可被 4 个基团 R 取代，这些基团可以相同或不同；T 代表 0 或 S；n 代表 1 或 2；m 代表 1、2 或 3；p代表1、2、3或4，L1和L2独立地代表CZ4Z5、NZ6、0、S、S(O)或S(0)2；R和Z1-Z6如权利要求中所定义；它们的制备过程和制备它们的中间化合物，它们作为杀真菌剂的用途，特别是以杀真菌组合物的形式，以及使用这些化合物或它们的组合物防治植物的植物病原真菌的方法。
• N-HETARYL(THIO)CARBONYL-2-(BENZOCYCLOALKEN-1 -YL)CYCLAMINES AND THEIR USE AS FUNGICIDES
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：EP3055296A1

  公开（公告）日：2016-08-17
• [EN] N-HETARYL(THIO)CARBONYL-2-(BENZOCYCLOALKEN-1 -YL)CYCLAMINES AND THEIR USE AS FUNGICIDES<br/>[FR] N-HÉTARYL(THIO)CARBONYL-2-(BENZOCYCLOALCÉN-1-YL)CYCLAMINES ET LEUR UTILISATION EN TANT QUE FONGICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2015052160A1

  公开（公告）日：2015-04-16

  The present invention relates to fungicidal N-hetarylcarbonyl-2- (benzocycloalken-1-yl) piperidines or pyrrolidines of formula (I), and their thiocarbonyl derivatives, wherein A represents a carbo-linked, unsaturated or partially saturated, 5- membered heterocyclyl group that can be substituted by up to four groups R that can be the same or different; T represents 0 or S; n represents 1 or 2; m represents 1, 2 or 3; p represents 1, 2, 3 or 4, L1 and L2 independently represent CZ4Z5, NZ6, 0, S, S(O) or S(0)2; and R and Z1 - Z6 are as defined in the claims; their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.