10-Aza-bicyclo<5.2.1>decan | 284-25-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环庚烷
• 英文名称: 10-Aza-bicyclo<5.2.1>decan
• 英文别名: 10-Azabicyclo[5.2.1]decane
• CAS: 284-25-3
• 化学式: C₉H₁₇N
• mdl: MFCD19221931
• 分子量: 139.241
• InChiKey: IUVNUEZWKZBSSC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE<br/>[FR] MONOBACTAMES ET PROCÉDÉS DE SYNTHÈSE ET D'UTILISATION DE CES DERNIERS
  申请人：HARVARD COLLEGE

  公开号：WO2015103583A1

  公开（公告）日：2015-07-09

  Described herein are monobactam antibiotics of Formula (I), (Ι'), (II), and (II'), along with methods and intermediates for preparing these compounds. Pharmaceutical compositions and methods of treating infectious diseases using the monobactams are also provided.

  本文描述了单环内酰胺抗生素的化学式(I)、(Ι')、(II)和(II')，以及制备这些化合物的方法和中间体。还提供了使用单环内酰胺治疗传染病的药物组合物和方法。
• Method for determining the surface characteristics of targets
  申请人：FORSCHUNGSZENTRUM JUELICH GMBH

  公开号：US10444156B2

  公开（公告）日：2019-10-15

  A method for in situ determination of surface characteristics of conductive targets includes generating a low-pressure plasma in front of a surface of a target, applying a voltage to the surface of the target, orientating at least one light-sensitive detector at an angle θ relative to a perpendicular to the surface of the target, and measuring an intensity of light emitted by electrically neutral atoms generated by conversion from ions which are accelerated out of the low-pressure plasma by the applied voltage toward the surface of the target and subsequently reflected thereon, and which thus exchange suitable charges with the surface to reach electrical neutrality. The method additionally includes determining a value curve comprising wavelengths and an intensity associated with each wavelength, of the light which, as a result of Doppler shifts, has a red-shifted wavelength range and a blue-shifted range.

  一种原位测定导电目标表面特性的方法包括在目标表面前产生低压等离子体，对目标表面施加电压，使至少一个光敏探测器以相对于垂直于目标表面的角度θ定向，测量由离子转换产生的电中性原子发出的光的强度，离子被施加的电压从低压等离子体中加速向目标表面发射，随后在目标表面反射，从而与表面交换适当的电荷以达到电中性。该方法还包括确定包括波长和与每个波长相关的强度的光值曲线，由于多普勒频移，该光具有红移波长范围和蓝移波长范围。
• MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE
  申请人：PRESIDENT AND FELLOWS OF HARVARD COLLEGE

  公开号：US20160326157A1

  公开（公告）日：2016-11-10

  Described herein are monobactam antibiotics of Formula (I), (I′), (II), and (II′), along with methods and intermediates for preparing these compounds. Pharmaceutical compositions and methods of treating infectious diseases using the monobactams are also provided.