4-(1-(吡咯啉-1-乙基)哌啶 | 933682-80-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 4-(1-(吡咯啉-1-乙基)哌啶
• 英文名称: 4-(1-(Pyrrolidin-1-yl)ethyl)piperidine
• 英文别名: 4-(1-pyrrolidin-1-ylethyl)piperidine
• CAS: 933682-80-5
• 化学式: C₁₁H₂₂N₂
• mdl: MFCD09055236
• 分子量: 182.31
• InChiKey: OWZYCRVGUAGGFJ-UHFFFAOYSA-N

物化性质

• 沸点：
  250.0±8.0 °C(Predicted)
• 密度：
  0.957±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

文献信息

• NOVEL THIENOPYRROLE COMPOUNDS
  申请人：Wishart Neil

  公开号：US20110152243A1

  公开（公告）日：2011-06-23

  The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

  该发明提供了公式（I）的化合物，包括药用盐、前药、生物活性代谢物、立体异构体和同分异构体，其中变量在此处定义。该发明的化合物可用于治疗免疫和肿瘤疾病。
• US9796711B2
  申请人：——

  公开号：US9796711B2

  公开（公告）日：2017-10-24
• [EN] SUBSTITUTED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXYLIC ACIDS AND THEIR USE<br/>[FR] ACIDES PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXYLIQUES SUBSTITUÉS ET LEUR UTILISATION
  申请人：ABBVIE S À R L

  公开号：WO2017060873A1

  公开（公告）日：2017-04-13

  The present invention provides for compounds of formula (I), wherein R1, R2, R3, and R4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sjögren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).