1,3-bis(methylselanyl)propan-2-ol | 1156548-46-7

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 1,3-bis(methylselanyl)propan-2-ol
• CAS: 1156548-46-7
• 化学式: C₅H₁₂OSe₂
• 分子量: 246.07
• InChiKey: NOHSIJBHEGVRQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.69
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  、 碘甲烷 在 氢氧化钾 、 一水合肼 作用下， 反应 2.0h， 以1.76 g的产率得到1,3-bis(methylselanyl)propan-2-ol
  参考文献：
  名称：

  Reactions of chloromethyloxirane and dihalopropanols with chalcogens in basic reducing systems

  摘要：

  Chloromethyloxirane and 2,3-dibromopropan-l-ol reacted with a solution of selenium or tellurium in the system hydrazin hydrate-potassium hydroxide (K2Se2, K2Te2) to give allyl alcohol; the reaction was accompanied by regeneration of the initial free chalcogen. 1,3-Dichloropropan-2-ol reacted with selenium in the same system to give oligomeric product having a 2-hydroxypropane-1,3-diyidiseleno monomeric unit, while the reaction with tellurium led to the formation of allyl alcohol and almost complete regeneration of initial tellurium. Probable reaction mechanisms are discussed. Polyselenide oligomers containing a hydroxy group in a monomeric unit were formed in reactions of chloromethyloxirane and 1,3-dichloropropan-2-ol with selenium in the system hydrazine hydrate-2-aininoethanol. Under analogous conditions 2,3-dibromopropan-l-ol was converted into allyl alcohol with regeneration of elemental selenium. Reductive cleavage of poly-selenide oligomers gave Se-methyl derivatives of 2-hydroxypropane-1,3-diselenol.

  DOI：

  10.1134/s1070428008040064