N,N,2,6-Tetramethylpiperidinium-jodid | 27644-31-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: N,N,2,6-Tetramethylpiperidinium-jodid
• 英文别名: 1,1,2,6-Tetramethylpiperidiniumiodid；1,1,2,6-Tetramethylpiperidin-1-ium;iodide
• CAS: 27644-31-1
• 化学式: C₉H₂₀N*I
• 分子量: 269.169
• InChiKey: LYJNIHQJTQRETP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.97
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Novel Method for Preparation of Ammonium Salts of Esomeprazole
  申请人：Bergman Rolf

  公开号：US20090197919A1

  公开（公告）日：2009-08-06

  The present invention relates to a process for the preparation of quartenary ammoniumsalts of esomeprazole. Further, the present invention also relates to the use quartenary ammoniumsalts of esomeprazole for the treatment of gastrointestinal disorders, pharmaceutical compositions containing them as well as the quartenary ammoniumsalts of esomeprazole, as such.

  本发明涉及一种制备左旋埃索美拉唑季铵盐的方法。此外，本发明还涉及使用左旋埃索美拉唑季铵盐治疗胃肠道疾病，含有其作为成分的制药组合物以及左旋埃索美拉唑季铵盐本身。
• NOVEL METHOD FOR PREPARATION OF AMMONIUM SALTS OF ESOMEPRAZOLE
  申请人：AstraZeneca AB

  公开号：EP2029574B1

  公开（公告）日：2010-12-01
• [EN] NOVEL METHOD FOR PREPARATION OF AMMONIUM SALTS OF ESOMEPRAZOLE<br/>[FR] NOUVEAU PROCÉDÉ POUR PRÉPARER DES SELS D'AMMONIUM D'ÉSOMÉPRAZOLE
  申请人：ASTRAZENECA AB

  公开号：WO2007142580A1

  公开（公告）日：2007-12-13

  [EN] The present invention relates to a process for the preparation of quartenary ammoniumsalts of esomeprazole. Further, the present invention also relates to the use quartenary ammoniumsalts of esomeprazole for the treatment of gastrointestinal disorders, pharmaceutical compositions containing them as well as the quartenary ammoniumsalts of esomeprazole, as such.
  [FR] La présente invention concerne un procédé pour préparer des sels d'ammonium quaternaires d'ésoméprazole. De plus, la présente invention concerne également l'utilisation de sels d'ammonium quaternaires d'ésoméprazole dans le traitement de troubles gastro-intestinaux, des compositions pharmaceutiques les contenant, ainsi que les sels d'ammonium quaternaires d'ésoméprazole en tant que tels.