ethyl 4-(5-methyl-6-(1-(4-(trifluoromethoxy)phenyl)ethylideneaminooxy)pyrimidin-4-yloxy)piperidine-1-carboxylate | 1190364-79-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: ethyl 4-(5-methyl-6-(1-(4-(trifluoromethoxy)phenyl)ethylideneaminooxy)pyrimidin-4-yloxy)piperidine-1-carboxylate
• 英文别名: Ethyl 4-[5-methyl-6-[1-[4-(trifluoromethoxy)phenyl]ethylideneamino]oxypyrimidin-4-yl]oxypiperidine-1-carboxylate
• CAS: 1190364-79-4
• 化学式: C₂₂H₂₅F₃N₄O₅
• 分子量: 482.46
• InChiKey: MTAHIUSKECMQLB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  34
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  95.4
• 氢给体数：
  0
• 氢受体数：
  11

文献信息

• [EN] OXIME DERIVATIVES<br/>[FR] DÉRIVÉS D'OXIME
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2009125434A2

  公开（公告）日：2009-10-15

  The present invention relates to novel oxime derivatives of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation.