4-(2-环己基乙基)-哌啶 | 62918-14-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 4-(2-环己基乙基)-哌啶
• 英文名称: 4-(2-Cyclohexylethyl)-piperidin
• 英文别名: 4-(2-Cyclohexylethyl)piperidine
• CAS: 62918-14-3
• 化学式: C₁₃H₂₅N
• 分子量: 195.348
• InChiKey: OKKFUFHNPJPJCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-(2-环己基乙基)-哌啶 、 5-氯-2-戊酮 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 生成 1-[4-(2-cyclohexylethyl)piperidino]pentan-4-one
  参考文献：
  名称：

  3-(Piperidino-lower-alkyl)-indoles

  摘要：

  1-酰基-3-(氨基-较低烷基)吲哚，作为抗炎药物有用，可以通过以下方式制备：通过对3-(氨基-较低烷基)吲哚进行酰化；通过从N'-酰基苯基肼和氨基-较低烷酮进行费舍尔吲哚合成；通过将胺基化合物与1-酰基-3-(卤代-较低烷基)吲哚进行烷基化；或通过还原烷基化1-酰基-3-吲哚-较低烷基羧醛。

  公开号：

  US04021431A1
• 作为产物：
  描述：

  trans-4-styrylpyride 在 盐酸 、 乙醇 、 铂 作用下， 生成 4-(2-环己基乙基)-哌啶
  参考文献：
  名称：

  Action of Metal Hydrides on β-(3-Indolyl)ethyl-1-pyridinium Salts^*1,2

  摘要：

  DOI：

  10.1021/jo01362a020

文献信息

• 1-Acyl-3-(amino-lower-alkyl)indoles
  申请人：Sterling Drug Inc.

  公开号：US04160862A1

  公开（公告）日：1979-07-10

  1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine and an amino-lower-alkanone; by alkylation of an amine with a 1-acyl-3-(halo-lower-alkyl)indole; or by reductive alkylation of a 1-acyl-3-indole-lower-alkylcarboxaldehyde.

  1-酰基-3-(氨基-低碳烷基)吲哚，可作为抗炎药物，可通过以下方法制备：将3-(氨基-低碳烷基)吲哚酰化；通过N'-酰基苯基腙和氨基-低碳烷酮的菲舍尔吲哚合成；通过胺与1-酰基-3-(卤代-低碳烷基)吲哚的烷基化；或者通过1-酰基-3-吲哚-低碳烷基羰基的还原烷基化。
• DERIVES DE 4-(CYCLOALKYL)PIPERIDINES ET DE 4-(CYCLOALKYLALKYL)PI PERIDINES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
  申请人：SYNTHELABO

  公开号：EP0848707A1

  公开（公告）日：1998-06-24
• Sulfonic acid group-containing organic-silica composite membrane and method for producing thereof
  申请人：Akiyama Eiichi

  公开号：US20070092776A1

  公开（公告）日：2007-04-26

  Problems of the invention are to provide an organic-silica complex-type electrolyte membrane which is expected to show electrolyte properties such as sufficient ion conductivity to be used in an electrochemical device, to have sufficient thermal resistance and mechanical strength in accordance with applications, to contain no halogen element which exerts a large environmental load, to be capable of being produced at low cost and, further, in view of being used in the electrochemical device, to suppress swelling even when impregnated with water, alcohol, a non-protonic polar solvent, an auxiliary electrolyte solution or the like, and, accordingly, to be excellent in a joining property and adhesiveness against an electrode, a method for producing the electrolyte membrane and the electrochemical device using the electrolyte membrane. To solve the problems, a production method for an organic-silica complex membrane having a sulfonic acid group which is characterized by having the steps of obtaining a sulfonic acid derivative by allowing an alkoxysilane compound having an amino group to react with a cyclic sultone and subjecting the sulfonic acid derivative to a condensation reaction is used.
• US3965105A
  申请人：——

  公开号：US3965105A

  公开（公告）日：1976-06-22
• US4008276A
  申请人：——

  公开号：US4008276A

  公开（公告）日：1977-02-15