3-(3,4-Dichlorophenyl)-2-(methoxymethyl)-8-azabicyclo[3.2.1]octane | 843660-54-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 3-(3,4-Dichlorophenyl)-2-(methoxymethyl)-8-azabicyclo[3.2.1]octane
• CAS: 843660-54-8
• 化学式: C₁₅H₁₉Cl₂NO
• 分子量: 300.2
• InChiKey: FPTPUYCHSWIWIB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• HYDROCHLORIDE SALT OF AN AZABICYCLO[3.2.1]OCTANE DERIVATIVE
  申请人：Grinter Trevor John

  公开号：US20100056561A1

  公开（公告）日：2010-03-04

  The invention relates to a hydrochloride salt of (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-[(methyloxy)methyl]-8-azabicyclo[3.2.1]octane, uses of the salt as a medicament in the treatment inter alia of disorders of the central nervous system and pharmaceutical compositions and dosage forms comprising the salt.
• TRANSDERMAL TROPANE COMPOSITIONS AND METHODS FOR USING THE SAME
  申请人：Saniona A/S

  公开号：US20220218689A1

  公开（公告）日：2022-07-14

  Aspects of the invention include transdermal delivery devices for delivering a tropane active agent to a subject. Also provided are methods of using the subject transdermal delivery devices, as well as kits containing one or more of the transdermal delivery devices.
• US8263611B2
  申请人：——

  公开号：US8263611B2

  公开（公告）日：2012-09-11