| 132814-50-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• CAS: 132814-50-7
• 化学式: C₂₆H₂₁LiO
• 分子量: 356.393
• InChiKey: QBHYRFXQFZNQIO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.61
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  在 水 作用下， 以 Petroleum ether 为溶剂， 反应 1.0h， 以100%的产率得到(三苯甲氧基甲基)苯
  参考文献：
  名称：

  C-Glycosides. 9. Stereospecific synthesis of C-glycosidic spiroketal of the papulacandins

  摘要：

  The reaction of ortho-lithiated triphenylmethyl benzyl ether with perbenzylated D-gluconolactone 1 followed by cyclization by BF3.Et2O provides a new stereospecific synthesis of C-glycosidic spiroketals. The structure of the peracetylated derivative was determined by X-ray diffraction. This methodology is applied to the synthesis of the spiroketal unit of papulacandins.

  DOI：

  10.1021/jo00022a014

文献信息

• C-Glycosides. 9. Stereospecific synthesis of C-glycosidic spiroketal of the papulacandins
  作者：Stanislas Czernecki、Marie Claude Perlat

  DOI：10.1021/jo00022a014

  日期：1991.10

  The reaction of ortho-lithiated triphenylmethyl benzyl ether with perbenzylated D-gluconolactone 1 followed by cyclization by BF3.Et2O provides a new stereospecific synthesis of C-glycosidic spiroketals. The structure of the peracetylated derivative was determined by X-ray diffraction. This methodology is applied to the synthesis of the spiroketal unit of papulacandins.