THIOPHENES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE
申请人:Gilbert Eric J.
公开号:US20120108505A1
公开(公告)日:2012-05-03
The present invention relates to compounds of the general formula (I): wherein R
1
, R
2
, R
3
, R
5
, s, and Z are selected independently of each other and are as defined herein, to compositions comprising the compounds, and methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.