Tert-butyl 3-(1,2,4-thiadiazol-5-yl)piperidine-1-carboxylate | 1364076-52-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: Tert-butyl 3-(1,2,4-thiadiazol-5-yl)piperidine-1-carboxylate
• CAS: 1364076-52-7
• 化学式: C₁₂H₁₉N₃O₂S
• 分子量: 269.368
• InChiKey: JHHPUTKPSRTGSJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  83.6
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Compounds and Compositions for Cognition-Enhancement, Methods of Making, and Methods of Treating
  申请人：NeuroSolis, Inc.

  公开号：US20170313687A1

  公开（公告）日：2017-11-02

  Disclosed are muscarinic agonist compounds including oxadiazole derivatives, compositions and preparations thereof. Also disclosed are methods of synthesizing such oxadiazole compounds. Further disclosed are methods for treating a subject with said muscarinic agonists or a pharmaceutically suitable form thereof to enhance cognitive function.