N(eq)-Benzyltropinonium | 37737-94-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: N(eq)-Benzyltropinonium
• 英文别名: N(ax)-Benzyltropinonium；8-Benzyl-8-methyl-8-azoniabicyclo[3.2.1]octan-3-one
• CAS: 37737-94-3
• 化学式: C₁₅H₂₀NO
• 分子量: 230.33
• InChiKey: HVERUTFJEKQRJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Quinolinone-carboxamide compounds
  申请人：Choi Seok-Ki

  公开号：US20060100426A1

  公开（公告）日：2006-05-11

  The invention provides novel quinolinone-carboxamide 5-HT 4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT 4 receptor activity, and processes and intermediates useful for preparing such compounds.

  这项发明提供了新型喹诺酮-羧酰胺5-HT4受体激动剂化合物。该发明还提供了包括这些化合物的药物组合物，使用这些化合物治疗与5-HT4受体活性相关疾病的方法，以及用于制备这些化合物的过程和中间体。
• Quinolinone compounds as 5-HT4 receptor agonists
  申请人：Goldblum A. Adam

  公开号：US20060199839A1

  公开（公告）日：2006-09-07

  The invention provides novel quinolinone-carboxamide 5-HT 4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT 4 receptor activity, and processes and intermediates useful for preparing such compounds.

  这项发明提供了新型喹诺酮-羧酰胺5-HT4受体激动剂化合物。该发明还提供了包括这些化合物的药物组合物，使用这些化合物治疗与5-HT4受体活性相关疾病的方法，以及用于制备这些化合物的过程和中间体。
• [EN] 3-BENZHYDRYLIDENE-8-AZA-BICYCLO[3.2.1]OCTANE DERIVATIVES WITH OPIOID RECEPTOR ACTIVITY<br/>[FR] DERIVES DE 3-BENZHYDRYLIDENE-8-AZA-BICYCLO[3.2.1]OCTANE A ACTIVITE DE RECEPTEUR D'OPIOIDES
  申请人：PFIZER PROD INC

  公开号：WO2004092165A1

  公开（公告）日：2004-10-28

  The present invention relates to compounds of the formula I, wherein R1, R2, and R3 are defined as in the specification, pharmaceutical compositions containing such compounds, and the use of such compounds to treat neurological and gastrointestinal disorders.

  本发明涉及公式I的化合物，其中R1、R2和R3如规范中所定义，包含这种化合物的药物组合物，以及利用这种化合物治疗神经和胃肠疾病。
• 5-HT4 receptor agonist compounds
  申请人：Choi Seok-Ki

  公开号：US20060100236A1

  公开（公告）日：2006-05-11

  The invention provides novel quinolinone-carboxamide 5-HT 4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT 4 receptor activity, and processes and intermediates useful for preparing such compounds.

  这项发明提供了新型的喹啉酮-羧酰胺5-HT4受体激动剂化合物。该发明还提供了包含这些化合物的药物组合物，使用这些化合物治疗与5-HT4受体活性相关的疾病的方法，以及用于制备这些化合物的过程和中间体。
• Benzoimidazolone-carboxamide compounds as 5-HT4 receptors agonists
  申请人：Gendron Roland

  公开号：US20060276482A1

  公开（公告）日：2006-12-07

  The invention provides novel benzoimidazolone-carboxamide 5-HT 4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT 4 receptor activity, and processes and intermediates useful for preparing such compounds.

  这项发明提供了新型苯并咪唑酮-羧酰胺5-HT4受体激动剂化合物。该发明还提供了包含这些化合物的药物组合物，使用这些化合物来治疗与5-HT4受体活性相关的疾病的方法，以及用于制备这些化合物的过程和中间体。