1-(ethylthio)-2-(hexamethyleneiminomethoxy)heptane | 1430214-52-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环庚烷
• 英文名称: 1-(ethylthio)-2-(hexamethyleneiminomethoxy)heptane
• 英文别名: 1-(1-Ethylsulfanylheptan-2-yloxymethyl)azepane；1-(1-ethylsulfanylheptan-2-yloxymethyl)azepane
• CAS: 1430214-52-0
• 化学式: C₁₆H₃₃NOS
• 分子量: 287.51
• InChiKey: MIZPHJHSKKQNMK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  37.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  环己亚胺 、 聚合甲醛 、 1-(ethylthio)heptane-2-ol 在 sodium hydroxide 作用下， 以 苯 为溶剂， 以74%的产率得到1-(ethylthio)-2-(hexamethyleneiminomethoxy)heptane
  参考文献：
  名称：

  Synthesis and antimicrobial activity of aminomethoxy-substituted 1-(ethylthio)heptanes

  摘要：

  The Mannich condensation of 1-(ethylthio)heptane-2-ol, formaldehyde and secondary amines taken in equimolar amounts gives rise to new aminomethoxy-substituted 1-(ethylthio)heptanes in a yield of 70-77%. The structure of the synthesized compounds was proved by the elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The compounds were tested as antimicrobial additives to lubricating oils. They were found to suppress effectively the activity of microorganisms.

  DOI：

  10.1134/s1070363213030134

文献信息

• Synthesis and antimicrobial activity of aminomethoxy-substituted 1-(ethylthio)heptanes
  作者：E. G. Mammadbeyli、I. A. Jafarov、S. I. Ibrahimli、T. G. Kyazimova、S. T. Alieva、G. F. Mamedova

  DOI：10.1134/s1070363213030134

  日期：2013.3

  The Mannich condensation of 1-(ethylthio)heptane-2-ol, formaldehyde and secondary amines taken in equimolar amounts gives rise to new aminomethoxy-substituted 1-(ethylthio)heptanes in a yield of 70-77%. The structure of the synthesized compounds was proved by the elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The compounds were tested as antimicrobial additives to lubricating oils. They were found to suppress effectively the activity of microorganisms.