4-[(3-硝基苯基)偶氮]苯胺 | 730-23-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 中文名称: 4-[(3-硝基苯基)偶氮]苯胺
• 英文名称: 3'-Nitroaminoazobenzol
• 英文别名: 4-(3-nitro-phenylazo)-aniline；4-(3-Nitro-phenylazo)-anilin；3'-Nitro-4-amino-azobenzol；(3-Nitro-benzol)-(1 azo 4)-anilin；Benzenamine, 4-[(3-nitrophenyl)azo]-；4-[(3-nitrophenyl)diazenyl]aniline
• CAS: 730-23-4
• 化学式: C₁₂H₁₀N₄O₂
• 分子量: 242.237
• InChiKey: MDMDJAOEKAAIGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  96.6
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-[(3-硝基苯基)偶氮]苯胺 在 乙醇 、 硫酸 、 sodium nitrite 作用下， 生成 (3-nitro-phenyl)-phenyl-diazene
  参考文献：
  名称：

  Meldola; Hanes, Chemical news and journal of industrial science, 1894, vol. 69, p. 309

  摘要：

  DOI：
• 作为产物：
  描述：

  3-nitrobenzenediazonium 生成 4-[(3-硝基苯基)偶氮]苯胺
  参考文献：
  名称：

  v.Mechel; Stauffer, Helvetica Chimica Acta, 1941, vol. 24, p. 151 E,152 E,153 E

  摘要：

  DOI：

文献信息

• Synthesis and QSAR modeling of 2-acetyl-2-ethoxycarbonyl-1-[4(4′-arylazo)-phenyl]-N,N-dimethylaminophenyl aziridines as potential antibacterial agents
  作者：Pratibha Sharma、Ashok Kumar、Siya Upadhyay、Vinita Sahu、Jitendra Singh

  DOI：10.1016/j.ejmech.2008.02.016

  日期：2009.1

  The present communication deals with the synthesis of a series of 2-acetyl-2-ethoxycarbonyl-1-[4(4'-arylazo)-phenyl]-N,N-dimethylaminophenyl aziridines. The compounds were synthesized in excellent yields (70-80%) and the structures were established on the basis of consistent IR, H-1 NMR and elemental analysis data. The purity has been ascertained by chromatographic resolution using acetic acid-toluene (6:4 v/v) as binary eluent. All the compounds have been tested for their antimicrobial activity against a representative panel of bacteria i.e. Bacillus subtilis, Escherichia coli, Pseudomonas diminuta and Staphylococcus aureus using azinomycin as reference drug. All the synthesized compounds were found to exhibit profound antimicrobial activity. (C) 2008 Elsevier Masson SAS. All rights reserved.
• Meldola, Journal of the Chemical Society, 1884, vol. 45, p. 116
  作者：Meldola

  DOI：——

  日期：——
• v.Mechel; Stauffer, Helvetica Chimica Acta, 1941, vol. 24, p. 151 E,152 E,153 E
  作者：v.Mechel、Stauffer

  DOI：——

  日期：——
• Meldola; Hanes, Chemical news and journal of industrial science, 1894, vol. 69, p. 309
  作者：Meldola、Hanes

  DOI：——

  日期：——