4-[(4-叠氮基-2,3,5,6-四氟苯甲酰基)氧基]-2,3,5,6-四氟苯磺酸钠盐

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 中文名称: 4-[(4-叠氮基-2,3,5,6-四氟苯甲酰基)氧基]-2,3,5,6-四氟苯磺酸钠盐
• 英文名称: sodium;4-(4-azido-2,3,5,6-tetrafluorobenzoyl)oxy-2,3,5,6-tetrafluorobenzenesulfonate
• 化学式: C₁₃F₈N₃O₅S*Na
• 分子量: 485.203
• InChiKey: NNHUPHMQAIKAQQ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.87
• 重原子数：
  31
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  106
• 氢给体数：
  0
• 氢受体数：
  15

反应信息

• 作为产物：
  描述：

  2,3,5,6-四氟苯酚 在 吡啶 、 硫酸 、 三氧化硫 作用下， 以 乙腈 为溶剂， 反应 24.0h， 生成 4-[(4-叠氮基-2,3,5,6-四氟苯甲酰基)氧基]-2,3,5,6-四氟苯磺酸钠盐
  参考文献：
  名称：

  4-Sulfotetrafluorophenyl (STP) esters: New water-soluble amine-reactive reagents for labeling biomolecules

  摘要：

  4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) esters of biopolymer-labeling molecules are shown to be dramatically more water-soluble than the corresponding N-hydroxysuccinimidyl (NHS) esters. These STP esters are easily synthesized, and react readily with primary amines to give the same acylation products as NHS and pentafluorophenyl (PFP) esters. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02695-1

文献信息

• 4-Sulfotetrafluorophenyl (STP) esters: New water-soluble amine-reactive reagents for labeling biomolecules
  作者：Kyle R. Gee、Eric A. Archer、Hee Chol Kang

  DOI：10.1016/s0040-4039(98)02695-1

  日期：1999.2

  4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) esters of biopolymer-labeling molecules are shown to be dramatically more water-soluble than the corresponding N-hydroxysuccinimidyl (NHS) esters. These STP esters are easily synthesized, and react readily with primary amines to give the same acylation products as NHS and pentafluorophenyl (PFP) esters. (C) 1999 Elsevier Science Ltd. All rights reserved.